Ampicillin
SIAL/PHR2838 - pharmaceutical secondary standard, certified reference material
Synonym: Ampicillin; D-(−)-α-Aminobenzylpenicillin
CAS Number: 69-53-4
Empirical Formula (Hill Notation): C16H19N3O4S
Molecular Weight: 349.40
MDL Number: MFCD00005175
Linear Formula: C16H19N3O4S
Product Type: Chemical
agency | traceable to Ph. Eur. A1000000 |
traceable to USP 1033000 | |
description | Pharmaceutical Secondary Standard; Certified Reference Material |
form | solid |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C16H19N3O4S/c1-16(2)11 |
InChI key | AVKUERGKIZMTKX-NJBDSQKTSA |
mp | 208 °C (dec.) (lit.) |
packaging | pkg of 500 mg |
SMILES string | [H][C@]12SC(C)(C)[C@@H](N |
storage temp. | 2-8°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | Mode of Action: Ampicillin is a semisynthetic penicillin and a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Antimicrobial Spectrum: Effective against both Gram-positive (similar to benzylpenicillin) and Gram-negative bacteria (similar to tetracyclines and chloramphenicol. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
mp | 208 °C (dec.) (lit.) |
Storage Temp. | 2-8°C |