Ampicillin

SIAL/PHR2838 - pharmaceutical secondary standard, certified reference material

Synonym: Ampicillin; D-(−)-α-Aminobenzylpenicillin

CAS Number: 69-53-4
Empirical Formula (Hill Notation): C₁₆H₁₉N₃O₄S
Molecular Weight: 349.40
MDL Number: MFCD00005175
Linear Formula: C₁₆H₁₉N₃O₄S
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-PHR2838-500MG	500 mg	$260.00 1/EA		Add To Favorites

Properties
Descriptions
Basic Data

agency	traceable to Ph. Eur. A1000000
	traceable to USP 1033000
description	Pharmaceutical Secondary Standard; Certified Reference Material
form	solid
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C16H19N3O4S/c1-16(2)11(15(22)23)19-13(21)10(14(19)24-16)18-12(20)9(17)8-6-4-3-5-7-8/h3-7,9-11,14H,17H2,1-2H3,(H,18,20)(H,22,23)/t9-,10-,11+,14-/m1/s1
InChI key	AVKUERGKIZMTKX-NJBDSQKTSA-N
mp	208 °C (dec.) (lit.)
packaging	pkg of 500 mg
SMILES string	[H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)c3ccccc3)C(O)=O
storage temp.	2-8°C

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.
Biochem/physiol Actions:	Mode of Action: Ampicillin is a semisynthetic penicillin and a ß-lactam antibiotic that inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Mode of Resistance: Administration with ß-lactamase cleaves the ß-lactam ring of Ampicillin and inactivates it. Antimicrobial Spectrum: Effective against both Gram-positive (similar to benzylpenicillin) and Gram-negative bacteria (similar to tetracyclines and chloramphenicol.
General description:	Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

mp	208 °C (dec.) (lit.)
Storage Temp.	2-8°C

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