Alosetron Hydrochloride
SIAL/PHR2990 - pharmaceutical secondary standard, certified reference material
Synonym: Alosetron hydrochloride; 2,3,4,5-
CAS Number: 122852-69-1
Empirical Formula (Hill Notation): C17H18N4O·HCl
Molecular Weight: 330.81
MDL Number: MFCD09028027
Linear Formula: C17H18N4O·HCl
Product Type: Chemical
application(s) | pharmaceutical |
CofA | current certificate can be downloaded |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C17H18N4O.ClH/c1-11-13 |
InChI key | FNYQZOVOVDSGJH-UHFFFAOYSA |
packaging | pkg of 500 mg |
SMILES string | CN1C2=C(C=CC=C2)C3=C1CCN( |
storage temp. | 2-30°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | Alosetron is a potent and highly selective antagonist of serotonin 5-HT3 receptors, nonselective cation channels found predominantly in the enteric nervous system of the gastrointestinal tract. These receptors are involved in the regulation of visceral pain, colonic transit and GI secretions that can contribute to the pathophysiology of irritable bowel syndrome (IBS). Alosetron is used clinically for treatment of women with severe diarrhea-predominant IBS. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Storage Temp. | 2-30°C |