Aminoglutethimide
SIAL/PHR3173 - pharmaceutical secondary standard, certified reference material
Synonym: DL-Aminoglutethimide; 3-
CAS Number: 125-84-8
Empirical Formula (Hill Notation): C13H16N2O2
Molecular Weight: 232.28
MDL Number: MFCD00010122
Linear Formula: C13H16N2O2
Product Type: Chemical
agency | traceable to BP BP684 |
traceable to USP 1025205 | |
application(s) | pharmaceutical |
CofA | current certificate can be downloaded |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C13H16N2O2/c1-2-13(8-7 |
InChI key | ROBVIMPUHSLWNV-UHFFFAOYSA |
mp | 152-154 °C (lit.) |
packaging | pkg of 500 mg |
SMILES string | CCC1(CCC(=O)NC1=O)c2ccc(N |
storage temp. | 2-30°C |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
Biochem/physiol Actions: | DL-Aminoglutethimide is a derivative of the sedative glutethimide. Originally introduced as an anticonvulsant, it was found to cause adrenal insufficiency. Blocks adrenal steroidogenesis by inhibiting the enzymatic conversion of cholesterol to pregnenolone. It also blocks the peripheral conversion (aromatization) of androgenic precursors to estrogens. The |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC8223 in the Documents slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 152-154 °C (lit.) |
Storage Temp. | 2-30°C |