Sulfasalazine
SIAL/S0883 - 97.0-101.5%
Synonym: 2-
CAS Number: 599-79-1
Empirical Formula (Hill Notation): C18H14N4O5S
Molecular Weight: 398.39
EC Number: 209-974-3
MDL Number: MFCD00057363
Linear Formula: C18H14N4O5S
Product Type: Chemical
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| assay | 97.0-101.5% |
| form | powder |
| InChI | 1S/C18H14N4O5S/c23-16-9-6 |
| InChI key | NCEXYHBECQHGNR-QZQOTICOSA |
| mode of action | DNA synthesis | interferes |
| enzyme | inhibits | |
| mp | 260-265 °C (dec.) (lit.) |
| Quality Level | 200  |
| SMILES string | OC(=O)c1cc(ccc1O)N=Nc2c |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Application: | Sulfasalazine has been used as an analytical standard in clinical studies: • For investigating its therapeutic potential in patients suffering from multiple sclerosis (MS). • For studying its role as an antiarthritic agent via inhibition of the cartilage degeneration and pain associated with progression of osteoarthritis in the rat, which is used as the test animal. It may also be used as an analytical reference standard for the quantification of the analyte in biological samples and aqueous samples using enzyme-linked immunosorbent assay (ELISA) and spectrofluorimetic technique. |
| General description: | Chemical structure: sulfonamide |
| General description: | Sulfasalazine (SSZ) belongs to the sulfonamide class of drugs, which can be metabolized into 5-aminosalicylic acid and sulfapyridine. SSZ is obtained as a reaction product of an antibacterial agent (sulfapyridine) and an anti-inflammatory agent (salicylic acid). |
| Packaging: | 10, 50, 100 g in glass bottle |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H317 - H334 |
| Precautionary statements | P261 - P280 - P284 - P304 + P340 - P333 + P313 - P342 + P311 |
| Hazard Codes | Xn |
| Risk Statements | 42/43 |
| Safety Statements | 22-29/56-45 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97.0-101.5% |
| mp | 260-265 °C (dec.) (lit.) |
| UNSPSC | 41116107 |