Scopolamine hydrobromide
SIAL/S0929 - meets USP testing specifications
Synonym: (−)-Scopolamine hydrobromide trihydrate; Hyoscine hydrobromide; Scopine tropate
CAS Number: 6533-68-2
Empirical Formula (Hill Notation): C17H21NO4 · HBr · 3H2O
Molecular Weight: 438.31
MDL Number: MFCD00150066
Linear Formula: C17H21NO4 · HBr · 3H2O
Product Type: Chemical
agency | meets USP testing specifications |
USP/NF | |
application(s) | pharmaceutical (small molecule) |
InChI | 1S/C17H21NO4.BrH.3H2O/c1- |
InChI key | LACQPOBCQQPVIT-SEYKEWMNSA |
mp | 195-199 °C (dry matter) (lit.) |
Quality Level | 200 ![]() |
SMILES string | O.O.O.Br.CN1[C@@H]2C[C@H] |
Application: | Scopolamine hydrobromide has been used as a muscarinic receptor antagonist: • to reverse the cardiac effects of physostigmine in rabbit heart • to study its effect on acoustic startle reflex (gap-PPI){148) • to study it’s in vitro antiviral, antibacterial, and antifungal activities and cytotoxicity • to study its effect on conditioning of lever pressing |
Biochem/physiol Actions: | Competitive nonselective muscarinic acetylcholine antagonist. Scopolamine-induced amnesia in laboratory animals is a commonly-used model of memory deficit. |
Packaging: | 1, 5, 25 g in glass bottle |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H300 + H310 + H330 |
Precautionary statements | P262 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 |
Hazard Codes | T+ |
Risk Statements | 26/27/28 |
Safety Statements | 25-45 |
RIDADR | UN 1544PSN2 6.1 / PGIII |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 195-199 °C (dry matter) (lit.) |
UNSPSC | 12352200 |