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N-Desethyl amodiaquine dihydrochloride

SIAL/SMB00947 - ≥95%

Synonym: Monodesethylamodiaquine dihydrochloride

CAS Number: 79049-30-2
Empirical Formula (Hill Notation): C18H18ClN3O · 2HCl
Molecular Weight: 400.73
Linear Formula: C18H18ClN3O · 2HCl
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-SMB00947-5MG 5 mg
$176.00
1/EA
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45-SMB00947-25MG 25 mg
$703.00
1/EA
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assay ≥95%
biological source synthetic
color yellow to dark yellow
form solid
Quality Level 200 
storage temp. 2-8°C
technique(s) HPLC: suitable
Application: Amodiaquine (AQ) is currently used in combination with Artesunate (AS) as first-line treatment for some cases of falciparum malaria (UM) in many countries. AQ is metabolized by hepatic cytochrome P450 2C8 (CYP2C8) to Desethylamodiaquine (DAQ; DEAQ; NADQ; Ndes-amo), which is subsequently eliminated via extra-hepatic biotransformation by CYP1A1 and CYP1B1. DEAQ is responsible for the pharmacological activity of AQ (both therapeutic and toxicity) due to its long elimination half-life.
Application: Metabolomics research
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95%
Storage Temp. 2-8°C
UNSPSC 12352200

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