4-Ethylphenol sodium sulfate
SIAL/SMB00971
Synonym: 4-Ethylphenyl sulfate sodium salt
Empirical Formula (Hill Notation): C8H9NaO4S
Molecular Weight: 224.21
Linear Formula: C8H9NaO4S
Product Type: Chemical
| assay | ≥98.0% (HPLC) |
| form | solid |
| Quality Level | 200  |
| storage temp. | −20°C |
| Application: | Metabolomics research Microbiome research |
| General description: | 4-Ethylphenol sodium sulfate is the sodium salt of 4-Ethylphenyl sulfate (4EPS). 4-Ethylphenyl sulfate is a gut microbial metabolite derived from tyrosine, which is converted into 4-ethylphenol and subsequently sulfated in the liver. Upregulated urine 4EPS levels are found among rats prone to insulin resistance and obesity. Increased plasma 4EPS was reported in a murine model of autism, and mice treated with 4EPS displayed anxiety-like behaviours. Higher levels of 4-ethylphenylsulfate were also found in plasma, liver, heart and kidneys in a rat model of chronic kidney disease. 4EPS is a component of the urine of male rats, and both 4-ethylphenyl sulfate and 4-ethylphenol are thought to participate in pheromonal communication. p-Cresol-sulfate and 4-ethylphenyl sulfate are thought to derive from tyrosine and have similar bioactivities, however their enzymatic production may differ. |
| Purity | ≥98.0% (HPLC) |
| Storage Temp. | −20°C |