Albendazole sulfoxide
SIAL/SMB01325 - ≥97% (HPLC)
Synonym: Ricobendazole; Albendazole oxide; Albendazole sulfoxide; Methyl [5-
CAS Number: 54029-12-8
Empirical Formula (Hill Notation): C12H15N3O3S
Molecular Weight: 281.33
MDL Number: MFCD00797922
Linear Formula: C12H15N3O3S
Product Type: Chemical
assay | ≥97% (HPLC) |
color | white to beige |
description | Modulation and Signaling |
form | solid |
InChI | 1S/C12H15N3O3S/c1-3-6-19( |
InChI key | VXTGHWHFYNYFFV-UHFFFAOYSA |
Quality Level | 100 ![]() |
SMILES string | CCCS(=O)c1ccc2[nH]c(NC(=O |
storage temp. | 2-8°C |
suitability | HPTLC |
Application: | Metabolomics research |
Biochem/physiol Actions: | Ricobendazole is a key metabolite of albendazole and acts as an anthelmintic. It has been shown to induce apoptosis in human cancer cell line HT-29, possibly by arresting cell cycle at the G2/M phase. |
General description: | Albendazole sulfoxide is a blood-brain barrier main metabolite of anti-parasitic agent albendazole that acts as a antihelminthic. It binds to colchicine binding site of β-tubulin and prevents polymerization. Albendazole sulfoxide exhibits greater affinity to parasitic β-tubulin than to mammalian. |
Symbol | ![]() ![]() ![]() |
Signal word | Warning |
Hazard statements | H317 - H361d - H373 - H410 |
Precautionary statements | P202 - P260 - P273 - P280 - P302 + P352 - P308 + P313 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥97% (HPLC) |
Storage Temp. | 2-8°C |