Trichloroacetic acid
SIAL/T4885 - ≥99.0% (titration)
Synonym: TCA
CAS Number: 76-03-9
Empirical Formula (Hill Notation): C2HCl3O2
Molecular Weight: 163.39
EC Number: 200-927-2
MDL Number: MFCD00004177
Linear Formula: Cl3CCOOH
Product Type: Chemical
assay | ≥99.0% (titration) |
bp | 196 °C (lit.) |
density | 1.62 g/mL at 25 °C (lit.) |
InChI | 1S/C2HCl3O2/c3-2(4,5)1(6) |
InChI key | YNJBWRMUSHSURL-UHFFFAOYSA |
mp | 54-58 °C (lit.) |
Quality Level | 200 ![]() |
refractive index | n |
SMILES string | OC(=O)C(Cl)(Cl)Cl |
solubility | H2O: 1 g/10 mL |
storage temp. | 2-8°C |
vapor density | <1 (vs air) |
vapor pressure | 1 mmHg ( 51 °C) |
Application: | Traditionally used to precipitate protein. Has been used to determine protein concentration by quantitative precipitation. Used as decalcifier and fixative in microscopy. |
Application: | Trichloroacetic acid (TCA) can be used as a catalyst to synthesize: • β-enaminones via condensation reaction of 1,3-dicarbonyl compounds and amines. • 6-amino-3-methyl-1,4-di • Tetrahydrobenzo[a]xanthen-11-ones by three-component reaction of aldehydes, 2-naphthol and dimedone. |
Packaging: | 1, 2 kg in glass bottle |
Packaging: | 500 g in glass bottle |
Symbol | ![]() ![]() ![]() |
Signal word | Danger |
Hazard statements | H314 - H335 - H410 |
Precautionary statements | P260 - P271 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 |
Hazard Codes | C,N |
Risk Statements | 35-50/53 |
Safety Statements | 26-36/37/39-45-60-61 |
RIDADR | UN 1839 8 / PGII |
WGK Germany | WGK 2 |
Flash Point(F) | 235.4 °F - closed cup |
Flash Point(C) | > 113 °C - closed cup |
Purity | ≥99.0% (titration) |
bp | 196 °C (lit.) |
mp | 54-58 °C (lit.) |
Density | 1.62 g/mL at 25 °C (lit.) |
Refractive Index | n |
Storage Temp. | 2-8°C |
UNSPSC | 12352100 |