Urea
SIAL/U1250 - ReagentPlus®, ≥99.5%, pellets
Synonym: Carbamide; Carbonyldiamide
CAS Number: 57-13-6
Empirical Formula (Hill Notation): CH4N2O
Molecular Weight: 60.06
EC Number: 200-315-5
MDL Number: MFCD00008022
Linear Formula: NH2CONH2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: U1250-1KG
This image depicts SKU: U1250-1KG
| assay | ≥99.5% |
| density | 1.335 g/mL at 25 °C (lit.) |
| form | pellets |
| InChI | 1S/CH4N2O/c2-1(3)4/h(H4,2 |
| InChI key | XSQUKJJJFZCRTK-UHFFFAOYSA |
| mp | 132-135 °C (lit.) |
| product line | ReagentPlus® |
| Quality Level | 300  |
| SMILES string | NC(N)=O |
| solubility | H2O: 8 M |
| Application: | Urea has been used as a protein denaturing agent. |
| Application: | Used for the denaturation of proteins and as a mild solubilization agent for insoluble or denatured proteins. Useful for renaturing proteins from samples already denatured with 6 M guanidine chloride such as inclusion bodies. May be used with guanidine hydrochloride and dithiothreitrol (DTT) in the refolding of denatured proteins into their native or active form. |
| General description: | Urea is a chaotropic agent and is used for protein denaturation. It disturbs the hydrogen bonds in the secondary, tertiary and quaternary structure of proteins. Urea can also disturb hydrogen bonds present in DNA secondary structure. |
| Legal Information: | ReagentPlus is a registered trademark of Sigma-Aldrich Co. LLC |
| Packaging: | 1 kg in poly bottle |
| Packaging: | 5 kg in poly drum |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.5% |
| mp | 132-135 °C (lit.) |
| Density | 1.335 g/mL at 25 °C (lit.) |
| UNSPSC | 12352100 |