Ethyl pyruvate

SIAL/W245735 - ≥97%, FG

Synonym: Ethyl 2-oxopropanoate; Ethyl 2-oxopropionate; Ethyl acetyl formate; Ethyl pyroracemate; Pyruvic acid ethyl ester

CAS Number: 617-35-6
Empirical Formula (Hill Notation): C₅H₈O₃
Molecular Weight: 116.12
EC Number: 210-511-2
MDL Number: MFCD00009123
Linear Formula: CH₃COCOOC₂H₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-W245735-250G-K	250 g	$92.90 1/EA	Add To Favorites
45-W245735-1KG-K	1 kg	$182.00 1/EA	Add To Favorites
45-W245735-10KG-K	10 kg	$1150.00 1/EA	Add To Favorites
45-W245735-25KG-K	25 kg	$2690.00 1/EA	Add To Favorites
45-W245735-SAMPLE-K		$56.20 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	meets purity specifications of JECFA
application(s)	flavors and fragrances
assay	≥97%
biological source	synthetic
bp	144 °C (lit.)
density	1.045 g/mL at 25 °C (lit.)
documentation	see Safety & Documentation for available documents
food allergen	no known allergens
grade	FG
	Halal
	Kosher
InChI	1S/C5H8O3/c1-3-8-5(7)4(2)6/h3H2,1-2H3
InChI key	XXRCUYVCPSWGCC-UHFFFAOYSA-N
organoleptic	fruity; ethereal; rum; sweet
Quality Level	400
refractive index	n20/D 1.404 (lit.)
reg. compliance	EU Regulation 1334/2008 & 178/2002
	FDA 21 CFR 117
	FDA 21 CFR 172.515
SMILES string	CCOC(=O)C(C)=O

Application:	High mobility group box 1 in the central nervous system: regeneration hidden beneath inflammation.: This study explores the role of high mobility group box 1 (HMGB1) in the central nervous system, focusing on its regenerative capabilities despite its inflammatory properties. Ethyl pyruvate was identified as a potential therapeutic agent in mitigating inflammation and promoting neural regeneration (Kim et al., 2025 ). Immunomodulation of Ethyl pyruvate on gestational diabetes mellitus in Mice; The impact on Th17/Treg balance.: This study investigates the effects of ethyl pyruvate on gestational diabetes mellitus (GDM) in mice, focusing on its immunomodulatory effects and its impact on the Th17/Treg balance, highlighting its potential benefits in managing GDM (Zhao et al., 2024 ). HMGB1/RAGE axis in tumor development: unraveling its significance.: The review delves into the HMGB1/RAGE axis in tumor development, examining its significance and the potential therapeutic role of ethyl pyruvate in targeting this pathway to inhibit tumor growth and progression (Fan et al., 2024 ). Ethyl pyruvate ameliorates acute respiratory distress syndrome in mice.: This article highlights the therapeutic potential of ethyl pyruvate in ameliorating acute respiratory distress syndrome (ARDS) in a mouse model, showcasing its anti-inflammatory and protective effects (Micanovic et al., 2024 ).
Packaging:	1 kg in poly bottle
Packaging:	10, 25 kg in poly drum
Packaging:	250 g in poly bottle

Symbol	GHS02,GHS05
Signal word	Danger
Hazard statements	H226 - H314
Precautionary statements	P210 - P233 - P240 - P280 - P303 + P361 + P353 - P305 + P351 + P338
RIDADR	UN 3272 3 / PGIII
WGK Germany	WGK 3
Flash Point(F)	114.8 °F - closed cup
Flash Point(C)	46 °C - closed cup

Purity	≥97%
bp	144 °C (lit.)
Density	1.045 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.404 (lit.)
FEMA Number	2457
UNSPSC	12164502

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