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Triton X-114

SIAL/X114 - laboratory grade

Synonym: (1,1,3,3-Tetramethylbutyl)phenyl-polyethylene glycol; Polyethylene glycol tert-octylphenyl ether

CAS Number: 9036-19-5
MDL Number: MFCD00128254
Linear Formula: (C2H4O)n C14H22O, n = 7 or 8
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-X114-100ML 100 mL
$41.50
1/EA
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45-X114-500ML 500 mL
$48.70
1/EA
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45-X114-1L 1 L
$93.20
1/EA
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45-X114-1GA 1 gal
$247.00
1/EA
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45-X114-5GA 5 gal
$769.00
1/EA
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CMC 0.2 mM (20-25°C)
composition t-Oct-C6H4-(OCH2CH2)xOH, x = 7-8
description non-ionic
grade laboratory grade
HLB 12.4
InChI 1S/C28H50O8/c1-27(2,3)24-28(4,5)25-6-8-26(9-7-25)36-23-22-35-21-20-34-19-18-33-17-16-32-15-14-31-13-12-30-11-10-29/h6-9,29H,10-24H2,1-5H3
InChI key HNLXNOZHXNSSPN-UHFFFAOYSA-N
mol wt average mol wt 537
Quality Level 200 
refractive index n20/D 1.488 (lit.)
SMILES string CC(C)(C)CC(C)(C)c1ccc(OCCOCCOCCOCCOCCOCCOCCO)cc1
transition temp cloud point 23 °C
  pour point ~−9 °C
Application: Triton X-114 has been used:
• To remove endotoxin from solutions of protein using phase separation technique
• In the extraction and purification of DNA from endotoxin
• In the biphasic extraction of lipoproteins from bacterial cell wall
• As a non-ionic detergent with a low cloud point (23 °C) enabling protein solubilization with phase-partitioning of hydrophilic from amphiphilic proteins
General description: Triton X-114 is a nonionic detergent. It is a good detergent for solubilizing membranes having reversible phase-separation property useful for the separation of intrinsic membrane proteins. Solution of Triton X-114 is homogeneous at 0°C but phase separation into aqueous phase and a detergent phase occurs above 20°C. Phase separation of proteins in solutions of Triton X-114 has been investigated. This octylphenol ethoxylate is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic & alkaline solutions.
Legal Information: Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow
Packaging: 1 gal in poly bottle
Packaging: 1 L in poly bottle
Packaging: 100, 500 mL in poly bottle
Packaging: 5 gal in poly drum
Refractive Index n20/D 1.488 (lit.)
UNSPSC 12161900

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