Triton™ X-114
SIAL/X114 - laboratory grade
Synonym: (1,1,3,3-
CAS Number: 9036-19-5
MDL Number: MFCD00128254
Linear Formula: (C2H4O)n C14H22O, n = 7 or 8
Product Type: Chemical
| CMC | 0.2 mM (20-25°C) |
| composition | t-Oct-C6H4-(OCH2CH2)xOH, x = 7-8 |
| description | non-ionic |
| grade | laboratory grade |
| HLB | 12.4 |
| InChI | 1S/C28H50O8/c1-27(2,3)24- |
| InChI key | HNLXNOZHXNSSPN-UHFFFAOYSA |
| mol wt | average mol wt 537 |
| Quality Level | 200 ![]() |
| refractive index | n |
| SMILES string | CC(C)(C)CC(C)(C)c1ccc(OCC |
| transition temp | cloud point 23 °C |
| pour point ~−9 °C |
| Application: | Triton™ X-114 has been used: • To remove endotoxin from solutions of protein using phase separation technique • In the extraction and purification of DNA from endotoxin • In the biphasic extraction of lipoproteins from bacterial cell wall • As a non-ionic detergent with a low cloud point (23 °C) enabling protein solubilization with phase-partitioning of hydrophilic from amphiphilic proteins |
| General description: | Triton™ X-114 is a nonionic detergent. It is a good detergent for solubilizing membranes having reversible phase-separation property useful for the separation of intrinsic membrane proteins. Solution of Triton™ X-114 is homogeneous at 0°C but phase separation into aqueous phase and a detergent phase occurs above 20°C. Phase separation of proteins in solutions of Triton™ X-114 has been investigated. This octylphenol ethoxylate is compatible with anionic, cationic, and other nonionic surfactants and chemically stable in most acidic & alkaline solutions. |
| Legal Information: | Triton is a trademark of The Dow Chemical Company or an affiliated company of Dow |
| Packaging: | 1 gal in poly bottle |
| Packaging: | 1 L in poly bottle |
| Packaging: | 100, 500 mL in poly bottle |
| Packaging: | 5 gal in poly drum |
| Symbol | ![]() ![]() GHS05,GHS07,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H318 - H410 |
| Precautionary statements | P264 - P273 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn,N |
| Risk Statements | 22-41-51/53 |
| Safety Statements | 26-39-61 |
| RIDADR | UN 3082 9 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 483.8 °F |
| Flash Point(C) | 251 °C |
| Refractive Index | n |
| UNSPSC | 12161900 |




