Acetylcholine chloride
SIAL/Y0000002 - European Pharmacopoeia (EP) Reference Standard
Synonym: ACh
CAS Number: 60-31-1
Empirical Formula (Hill Notation): C7H16ClNO2
Molecular Weight: 181.66
EC Number: 200-468-8
MDL Number: MFCD00011698
Linear Formula: (CH3)3N+CH2CH2OCOCH3Cl-
Product Type: Chemical
| API family | acetylcholine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C7H16NO2.ClH/c1-7(9)10 |
| InChI key | JUGOREOARAHOCO-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| mp | 146-150 °C (lit.) |
| SMILES string | [Cl-].CC(=O)OCC[N+](C)(C) |
| storage temp. | −20°C |
| Application: | Acetylcholine chloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
| Biochem/physiol Actions: | Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergic anti-inflammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 146-150 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 41116107 |