Synonym: (−)-Tetramisole hydrochloride; (S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride; L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride; Levamisole hydrochloride
CAS Number: 16595-80-5
Empirical Formula (Hill Notation): C11H12N2S · HCl
Molecular Weight: 240.75
MDL Number: MFCD00012675
Linear Formula: C11H12N2S · HCl
Product Type: Chemical
| API family |
levamisole |
| application(s) |
pharmaceutical (small molecule) |
| format |
neat |
| grade |
pharmaceutical primary standard |
| InChI |
1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
| InChI key |
LAZPBGZRMVRFKY-HNCPQSOCSA-N |
| manufacturer/tradename |
EDQM |
| mp |
228-230 °C |
| SMILES string |
Cl.C1CN2C[C@@H](N=C2S1)c3ccccc3 |
| storage temp. |
2-8°C |
| Application: |
Levamisole hydrochloride for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
| Biochem/physiol Actions: |
Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors. Very effective in treatment of ascariasis (hookworm infestation). Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages. |
| General description: |
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: |
Sales restrictions may apply. |
| Packaging: |
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |
 GHS06 |
| Signal word |
Danger |
| Hazard statements |
H301 |
| Precautionary statements |
P301 + P330 + P331 + P310 |
| RIDADR |
UN 2811 6.1 / PGIII |
| WGK Germany |
WGK 3 |
| Flash Point(F) |
Not applicable |
| Flash Point(C) |
Not applicable |
| mp |
228-230 °C |
| Storage Temp. |
2-8°C |
| UNSPSC |
41116107 |
