Thimerosal
SIAL/Y0000109 - European Pharmacopoeia (EP) Reference Standard
Synonym: 2-
CAS Number: 54-64-8
Empirical Formula (Hill Notation): C9H9HgNaO2S
Molecular Weight: 404.81
MDL Number: MFCD00013062
Linear Formula: 2-(C2H5HgS)C6H4CO2Na
Product Type: Chemical
| API family | thimerosal |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C7H6O2S.C2H5.Hg.Na/c8- |
| InChI key | RTKIYNMVFMVABJ-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| mp | 234-237 °C (dec.) (lit.) |
| SMILES string | [Na+].CC[Hg]Sc1ccccc1C([O |
| storage temp. | 2-8°C |
| Application: | Thimerosal EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
| Biochem/physiol Actions: | Thimerosal is a sulfhydryl (thiol) oxidizing reagent capable of inhibiting a wide range of sulfhydryl-dependent enzymes and proteins such as PI3-kinase-dependent methionine synthase, glutamate transport receptors, and Na++K+ dependent ATPases. |
| Disclaimer: | As part of the corporation global plan to support the Minamata Convention in eliminating mercury-containing compounds, as of January 2021 customers will be required to provide an End-Use Declaration. The sales of thimerosal will be restricted for approved applications only, such as preservative in vaccine manufacturing, preservative in eye cosmetics, research use within academia (excluding preservation intent) and as reference material only. The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act , European Biocidal Products Regulation, Canada′s Pest Management Regulatory Agency, Turkey′s Biocidal Products Regulation, Korea′s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H300 + H310 + H330 - H373 - H410 |
| Precautionary statements | P262 - P273 - P280 - P301 + P310 + P330 - P302 + P352 + P310 - P304 + P340 + P310 |
| RIDADR | UN 2025 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 482.0 °F - closed cup |
| Flash Point(C) | 250 °C - closed cup |
| mp | 234-237 °C (dec.) (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |