Synonym: Perindopril erbumine; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]-1-oxopropyl]octahydro-1H-indole-2-carboxylic acid tert-butylamine salt; Perindopril tert-butylamine; S-9490
CAS Number: 107133-36-8
Empirical Formula (Hill Notation): C19H32N2O5 · C4H11N
Molecular Weight: 441.60
MDL Number: MFCD02313824
Linear Formula: C19H32N2O5 · C4H11N
Product Type: Chemical
application(s) |
pharmaceutical (small molecule) |
format |
neat |
grade |
pharmaceutical primary standard |
InChI |
1S/C19H32N2O5.C4H11N/c1-4-8-14(19(25)26-5-2)20-12(3)17(22)21-15-10-7-6-9-13(15)11-16(21)18(23)24;1-4(2,3)5/h12-16,20H,4-11H2,1-3H3,(H,23,24);5H2,1-3H3/t12-,13-,14-,15-,16-;/m0./s1 |
InChI key |
IYNMDWMQHSMDDE-MHXJNQAMSA-N |
manufacturer/tradename |
EDQM |
SMILES string |
CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(O)=O)C(=O)OCC |
storage temp. |
2-8°C |
Biochem/physiol Actions: |
Perindopril erbumine is an angiotensin converting enzyme (ACE) inhibitor; antihypertensive; becomes hydrolyzed in vivo to the active diacid metabolite; unlike the other ACE inhibitors, inhibits tumor growth in hepatocellular carcinoma cells due to suppression of VEGF levels; also suppresses angiotensin II production in vitro. Long-term therapy with this agent has a beneficial effect on the cerebral circulation by improving cerebral perfusion reserve in patients with previous minor stroke. |
Caution: |
Please find SDS provided by EDQM here. . |
General description: |
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: |
Sales restrictions may apply. |
Packaging: |
Unit quantity: 40 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
RIDADR |
NONH for all modes of transport |
WGK Germany |
WGK 3 |
Flash Point(F) |
Not applicable |
Flash Point(C) |
Not applicable |
Storage Temp. |
2-8°C |
UNSPSC |
41116107 |