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Lamivudine for system suitability 2

SIAL/Y0000426 - European Pharmacopoeia (EP) Reference Standard

Synonym: Lamivudine; 2′,3′-Dideoxy-3′-thiacytidine; 3TC; Epivir; Epivir-HBV; Heptovir; Zeffix

CAS Number: 134678-17-4
Empirical Formula (Hill Notation): C8H11N3O3S
Molecular Weight: 229.26
MDL Number: MFCD00869739
Linear Formula: C8H11N3O3S
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0000426 10.3 mg
 $150.00
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API family lamivudine
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C8H11N3O3S/c9-5-1-2-11(8(13)10-5)6-4-15-7(3-12)14-6/h1-2,6-7,12H,3-4H2,(H2,9,10,13)/t6-,7+/m0/s1
InChI key JTEGQNOMFQHVDC-NKWVEPMBSA-N
manufacturer/tradename EDQM
SMILES string NC1=NC(=O)N(C=C1)[C@@H]2CS[C@H](CO)O2
storage temp. 2-8°C
Application: Lamivudine for system suitability 2 EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions: Lamivudine is a potent nucleoside analog reverse transcriptase inhibitor (nRTI). It is an analogue of cytidine, and can inhibit both types (1 and 2) of HIV reverse transcriptase as well as the reverse transcriptase of hepatitis B. It needs to be phosphorylated to its triphosphate form before it is active. 3TC-triphosphate also inhibits cellular DNA polymerase.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 41116107

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