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Glutathione

SIAL/Y0000517 - European Pharmacopoeia (EP) Reference Standard

Synonym: L-Glutathione reduced; γ-L-Glutamyl-L-cysteinyl-glycine; GSH

CAS Number: 70-18-8
Empirical Formula (Hill Notation): C10H17N3O6S
Molecular Weight: 307.32
MDL Number: MFCD00065939
Linear Formula: H2NCH(CO2H)CH2CH2CONHCH(CH2SH)CONHCH2CO2H
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0000517 10 mg
 $220.00
1/EA		 Add To Favorites

 

API family glutathione
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChI key RWSXRVCMGQZWBV-WDSKDSINSA-N
manufacturer/tradename EDQM
mp 192-195 °C (dec.) (lit.)
SMILES string N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
storage temp. 2-8°C
Amino Acid Sequence: γ-Glu-Cys-Gly
Application: May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.
Biochem/physiol Actions: Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
mp 192-195 °C (dec.) (lit.)
Storage Temp. 2-8°C
UNSPSC 41116107

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