Amitriptyline hydrochloride
SIAL/Y0000563 - European Pharmacopoeia (EP) Reference Standard
Synonym: AMT
CAS Number: 549-18-8
Empirical Formula (Hill Notation): C20H23N · HCl
Molecular Weight: 313.86
MDL Number: MFCD00012537
Linear Formula: C20H23N · HCl
Product Type: Chemical
API family | amitriptyline |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C20H23N.ClH/c1-21(2)15 |
InChI key | KFYRPLNVJVHZGT-UHFFFAOYSA |
manufacturer/tradename | EDQM |
SMILES string | Cl[H].CN(C)CCC=C1c2cccc |
storage temp. | 2-8°C |
Application: | Amitriptyline hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
Biochem/physiol Actions: | Tricyclic antidepressant; inhibits the norepinephrine and serotonin transporters with Kis of 100 nM and 14.7 nM, respectively; high in vitro affinity for α1-adrenoceptors, serotonin and muscarinic acetylcholine receptors. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
Symbol | GHS06,GHS08,GHS09 |
Signal word | Danger |
Hazard statements | H301 - H319 - H361d - H410 |
Precautionary statements | P201 - P273 - P301 + P310 + P330 - P305 + P351 + P338 |
RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |