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Thioctic acid for system suitability

SIAL/Y0000592 - European Pharmacopoeia (EP) Reference Standard

Synonym: (±)-α-Lipoic acid; (±)-1,2-Dithiolane-3-pentanoic acid; 6,8-Dithiooctanoic acid; DL-α-Lipoic acid; DL-6,8-Thioctic acid; Lip(S2)

CAS Number: 1077-28-7
Empirical Formula (Hill Notation): C8H14O2S2
Molecular Weight: 206.33
MDL Number: MFCD00005474
Linear Formula: C8H14O2S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0000592 15 mg
 $220.00
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API family thioctic acid
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
InChI key AGBQKNBQESQNJD-UHFFFAOYSA-N
manufacturer/tradename EDQM
SMILES string OC(=O)CCCCC1CCSS1
storage temp. 2-8°C
Application: Thioctic acid for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions: Antioxidant and coenzyme needed for the activity of enzyme complexes such as those of pyruvate dehydrogenase and glycine decarboxylase. Exogenous thioctic acid is reduced intracellularly by two or more enzymes. The reduced form then influences a number of cell processes by direct radical scavenging, recycling of other antioxidants, increasing glutathione synthesis, and modulating transcription factor activity particularly that of NF-κB. Decreases the phagocytosis of myelin by macrophages.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
Storage Temp. 2-8°C
UNSPSC 41116107

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