Capsaicin
SIAL/Y0000671 - European Pharmacopoeia (EP) Reference Standard
Synonym: 8-Methyl-N-vanillyl-trans-6-nonenamide
CAS Number: 404-86-4
Empirical Formula (Hill Notation): C18H27NO3
Molecular Weight: 305.41
EC Number: 206-969-8
MDL Number: MFCD00017259
Linear Formula: (CH3)2CHCH=CH(CH2)4CONHCH2C6H3-4-(OH)-3-(OCH3)
Product Type: Chemical
agency | EP Reference Standard |
API family | capsaicin |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C18H27NO3/c1-14(2)8-6- |
InChI key | YKPUWZUDDOIDPM-SOFGYWHQSA |
manufacturer/tradename | EDQM |
mp | 62-65 °C (lit.) |
SMILES string | COc1cc(CNC(=O)CCCCC=CC( |
storage temp. | 2-8°C |
Application: | Capsaicin EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
Biochem/physiol Actions: | Prototype vanilloid receptor agonist. Neurotoxin; activates sensory neurons that give rise to unmyelinated C-fibers, many of which contain substance P. Topical application desensitizes the sensory nerve endings giving a paradoxical antinociceptive effect; systemic administration can be neurotoxic to capsaicin-sensitive cells, especially in newborn animals. Active component of chili peppers. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
Symbol | GHS05,GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H300 - H315 - H317 - H318 - H334 - H335 |
Precautionary statements | P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 + P310 |
RIDADR | UN 1544PSN1 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | 235.4 °F - closed cup |
Flash Point(C) | 113 °C - closed cup |
mp | 62-65 °C (lit.) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |