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Berberine chloride

SIAL/Y0001149 - European Pharmacopoeia (EP) Reference Standard

Synonym: Berberine chloride form; Natural Yellow 18

CAS Number: 633-65-8
Empirical Formula (Hill Notation): C20H18ClNO4
Molecular Weight: 371.81
MDL Number: MFCD00011939
Linear Formula: C20H18ClNO4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0001149 20 mg
 $220.00
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API family berberine
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
InChI key VKJGBAJNNALVAV-UHFFFAOYSA-M
manufacturer/tradename EDQM
SMILES string COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
storage temp. 2-8°C
Application: Fluorescent stain for heparin in mast cells
Biochem/physiol Actions: An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
Colour Index Number 75160
UNSPSC 41116107

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