Dexamethasone for system suitability
SIAL/Y0001177 - European Pharmacopoeia (EP) Reference Standard
Synonym: Dexamethasone; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F
CAS Number: 50-02-2
Empirical Formula (Hill Notation): C22H29FO5
Molecular Weight: 392.46
MDL Number: MFCD00064136
Linear Formula: C22H29FO5
Product Type: Chemical
agency | EP |
application(s) | pharmaceutical (small molecule) |
biological source | synthetic |
form | powder |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C22H29FO5/c1-12-8-16-1 |
InChI key | UREBDLICKHMUKA-CXSFZGCWSA |
manufacturer/tradename | EDQM |
mp | 262-264 °C |
262-264 °C (lit.) | |
packaging | pkg of 10 mg |
shipped in | ambient |
SMILES string | C[C@@H]1C[C@H]2[C@@H]3CCC |
solubility | water: <0.1 g/L |
storage condition | protect from light |
storage temp. | 2-8°C |
Application: | Dexamethasone is used as a pharmaceutical primary standard to quantify the analyte in pharmaceutical formulations using liquid chromatography (LC) technique. |
Biochem/physiol Actions: | Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase. |
Caution: | Please find SDS provided by EDQM here. ![]() ![]() |
General description: | Dexamethasone belongs to the class of synthetic glucocorticoid steroid drugs. This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia ![]() ![]() |
Other Notes: | Sales restrictions may apply. |
Packaging: | Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue ![]() ![]() |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H360FD |
Precautionary statements | P201 - P202 - P280 - P308 + P313 - P405 - P501 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 262-264 °C (lit.); 262-264 °C |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |