Flucytosine for system suitability
SIAL/Y0001262 - European Pharmacopoeia (EP) Reference Standard
Synonym: 5-Fluorocytosine; 4-
CAS Number: 2022-85-7
Empirical Formula (Hill Notation): C4H4FN3O
Molecular Weight: 129.09
MDL Number: MFCD00006035
Linear Formula: C4H4FN3O
Product Type: Chemical
| API family | flucytosine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C4H4FN3O/c5-2-1-7-4(9) |
| InChI key | XRECTZIEBJDKEO-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| mp | 298-300 °C (dec.) (lit.) |
| SMILES string | NC1=NC(=O)NC=C1F |
| storage temp. | 2-8°C |
| Application: | Flucytosine for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
| Biochem/physiol Actions: | Nucleoside analog that has antifungal activities. 5-FC is deaminated by cytosine deaminase to product 5-fluorouracil, resulting in RNA miscoding. 5-Fluorocytosine inhibits DNA and RNA synthesis and interferes with ribosomal protein synthesis. |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |  GHS08 |
| Signal word | Warning |
| Hazard statements | H361 |
| Precautionary statements | P280 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 298-300 °C (dec.) (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |