Etoposide for system suitability
SIAL/Y0001365 - European Pharmacopoeia (EP) Reference Standard
Synonym: Etoposide; 4′-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside); VP-16-213
CAS Number: 33419-42-0
Empirical Formula (Hill Notation): C29H32O13
Molecular Weight: 588.56
MDL Number: MFCD00869325
Linear Formula: C29H32O13
Product Type: Chemical
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C29H32O13/c1-11-36-9-2 |
InChI key | VJJPUSNTGOMMGY-MRVIYFEKSA |
manufacturer/tradename | EDQM |
SMILES string | COc1cc(cc(OC)c1O)[C@H]2[C |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Etoposide is an antitumor agent that complexes with topoisomerase II and DNA to enhance double-strand and single-strand cleavage of DNA and reversibly inhibit religation. Blocks the cell cycle in in S-phase and G2-phase of the cell cycle; induces apoptosis in normal and tumor cell lines; inhibits synthesis of the oncoprotein Mdm2 and induces apoptosis in tumor lines that overexpress Mdm2. |
Caution: | Please find SDS provided by EDQM here. ![]() ![]() |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia ![]() ![]() |
Other Notes: | Sales restrictions may apply. |
Packaging: | Unit quantity: 10 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue ![]() ![]() |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H302 - H350 - H361d |
Precautionary statements | P201 - P202 - P264 - P270 - P301 + P312 - P308 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |