Anhydrous Docetaxel
SIAL/Y0001466 - European Pharmacopoeia (EP) Reference Standard
Synonym: Docetaxel
CAS Number: 114977-28-5
Empirical Formula (Hill Notation): C43H53NO14
Molecular Weight: 807.88
MDL Number: MFCD00800737
Linear Formula: C43H53NO14
Product Type: Chemical
API family | docetaxel |
application(s) | pharmaceutical (small molecule) |
format | neat |
grade | pharmaceutical primary standard |
InChI | 1S/C43H53NO14/c1-22-26(55 |
InChI key | ZDZOTLJHXYCWBA-VCVYQWHSSA |
manufacturer/tradename | EDQM |
mp | 186-192 °C (dec.) |
SMILES string | [H][C@@]12C[C@H](O)[C@@]3 |
storage temp. | 2-8°C |
Application: | Anhydrous Docetaxel EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
Biochem/physiol Actions: | Docetaxel is a taxane anti-cancer agent related to paclitaxel. It binds to and stabilizes the β−tubulin subunit of microtubules, preventing depolymerization of the mitotic spindle thus leading to cell cycle arrest and apoptosis. |
General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia . |
Other Notes: | Sales restrictions may apply. |
Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
Symbol | GHS07,GHS08 |
Signal word | Danger |
Hazard statements | H319 - H341 - H360D - H362 - H372 |
Precautionary statements | P201 - P202 - P260 - P263 - P305 + P351 + P338 - P308 + P313 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
mp | 186-192 °C (dec.) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |