Atovaquone for system suitability

SIAL/Y0001573 - European Pharmacopoeia (EP) Reference Standard

Synonym: Atovaquone; Mepron; trans-2-[4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthalenedione

CAS Number: 95233-18-4
Empirical Formula (Hill Notation): C₂₂H₁₉ClO₃
Molecular Weight: 366.84
Linear Formula: C₂₂H₁₉ClO₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-Y0001573	15 mg	$153.00 1/EAAdd To Favorites		Add To Favorites

API family	atovaquone
application(s)	pharmaceutical (small molecule)
format	neat
grade	pharmaceutical primary standard
InChI	1S/C22H19ClO3/c23-16-11-9-14(10-12-16)13-5-7-15(8-6-13)19-20(24)17-3-1-2-4-18(17)21(25)22(19)26/h1-4,9-13,15,26H,5-8H2/t13-,15-
InChI key	KUCQYCKVKVOKAY-CTYIDZIISA-N
manufacturer/tradename	EDQM
SMILES string	OC1=C([C@H]2CC[C@@H](CC2)c3ccc(Cl)cc3)C(=O)c4ccccc4C1=O
storage temp.	2-8°C

Application:	Atovaquone for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions:	Atovaquone is an anti-protozoal mitochondrial electron transport inhibitor; Antimalarial; Antipneumocystic, and has also been used to treat toxoplasmosis. It is an analog of protozoan mitochondrial protein ubiquinone, and acts by inhibiting the cytochrome bc(1) complex via interactions with the Rieske iron-sulfur protein and cytochrome b in the ubiquinol oxidation pocket.
General description:	This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes:	Sales restrictions may apply.
Packaging:	The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .