Synonym: Dexamethasone; (11β,16α)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione; 9α-Fluoro-16α-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione; 9α-Fluoro-16α-methylprednisolone; Prednisolone F
CAS Number: 50-02-2
Empirical Formula (Hill Notation): C22H29FO5
Molecular Weight: 392.46
MDL Number: MFCD00064136
Linear Formula: C22H29FO5
Product Type: Chemical
| agency |
EP |
| API family |
dexamethasone |
| application(s) |
pharmaceutical (small molecule) |
| biological source |
synthetic |
| form |
powder |
| format |
neat |
| grade |
pharmaceutical primary standard |
| InChI |
1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 |
| InChI key |
UREBDLICKHMUKA-CXSFZGCWSA-N |
| manufacturer/tradename |
EDQM |
| mp |
262-264 °C |
| |
262-264 °C (lit.) |
| shipped in |
ambient |
| SMILES string |
C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO |
| solubility |
water: <0.1 g/L |
| storage condition |
protect from light |
| storage temp. |
2-8°C |
| Application: |
Dexamethasone is used as an EP referencs standard to quantify the analyte in pharmaceutical formulations using liquid chromatography (LC) technique. |
| Biochem/physiol Actions: |
Glucocorticoid anti-inflammatory agent. Regulates T cell survival, growth, and differentiation. Inhibits the induction of nitric oxide synthase. |
| General description: |
Dexamethasone belongs to the class of synthetic glucocorticoid steroid drugs.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: |
Sales restrictions may apply. |
| Packaging: |
The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| mp |
262-264 °C (lit.); 262-264 °C |
| Storage Temp. |
2-8°C |
| UNSPSC |
41116107 |
