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Ropinirole hydrochloride

SIAL/Y0001773 - European Pharmacopoeia (EP) Reference Standard

Synonym: 4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride; SKF 101468 hydrochloride

CAS Number: 91374-20-8
Empirical Formula (Hill Notation): C16H24N2O · HCl
Molecular Weight: 296.84
MDL Number: MFCD01754173
Linear Formula: C16H24N2O · HCl
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0001773 125 mg
 $150.00
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API family ropinirole
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C16H24N2O.ClH/c1-3-9-18(10-4-2)11-8-13-6-5-7-15-14(13)12-16(19)17-15;/h5-7H,3-4,8-12H2,1-2H3,(H,17,19);1H
InChI key XDXHAEQXIBQUEZ-UHFFFAOYSA-N
manufacturer/tradename EDQM
SMILES string Cl.CCCN(CCC)CCc1cccc2NC(=O)Cc12
storage temp. 2-8°C
Application: Ropinirole hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions: An agonist at the D2 and D3 dopamine receptor subtypes, binding with higher affinity to D3 than to D2 or D4. It has negligible effect on D1-receptors. It has medium in vitro affinity to opioid receptors. Ropinirole is said to have virtually no affinity to 5-HT1, 5-HT2, benzodiazepine, GABA, muscarinic, α1-, α2-, and β-adrenoreceptors. Used as antiparkinsonian drug.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
Symbol GHS07GHS09  GHS07,GHS09
Signal word Warning
Hazard statements H302 - H400
Precautionary statements P301 + P312 + P330
RIDADR UN 3077 9 / PGIII
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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