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Dienogest

SIAL/Y0001785 - European Pharmacopoeia (EP) Reference Standard

Synonym: (17a)-17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-Hydroxy-3-oxo-19-norpregna-4,9-diene-21-nitrile; 17-cyanomethyl-17-hydroxy-estra-4,9-dien-3-one

CAS Number: 65928-58-7
Empirical Formula (Hill Notation): C20H25NO2
Molecular Weight: 311.42
MDL Number: MFCD00868356
Linear Formula: C20H25NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-Y0001785 80 mg
 $153.00
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API family dienogest
application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C20H25NO2/c1-19-8-6-16-15-5-3-14(22)12-13(15)2-4-17(16)18(19)7-9-20(19,23)10-11-21/h12,17-18,23H,2-10H2,1H3/t17-,18+,19+,20-/m1/s1
InChI key AZFLJNIPTRTECV-FUMNGEBKSA-N
manufacturer/tradename EDQM
SMILES string O[C@@]1(CC#N)CC[C@@]2([H])[C@]3([H])CCC4=CC(CCC4=C3CC[C@@]21C)=O
storage temp. 2-8°C
Application: Dienogest EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.
Biochem/physiol Actions: Dienogest is a fourth-generation progestin, an orally active synthetic progestogen with approximately 10% of the relative affinity of progesterone, but has a very potent progestagenic effect in the endometrium with some antiandrogenic activity and without any androgenic, glucocorticoid or mineralocorticoid effects. It has been used alone or in combination as a contraceptive and to treat uterine fibroids. Dienogest inhibits ovulation primarily through peripheral action rather than by central action on gonadotrophin secretion.
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including MSDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
Symbol GHS08  GHS08
Signal word Warning
Hazard statements H361
Precautionary statements P280
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Storage Temp. 2-8°C
UNSPSC 12352200

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