Ethyl acetate

SIGALD/27227 - puriss., meets analytical specification of Ph. Eur., BP, NF, ≥99.5% (GC)

Synonym: EtOAc

CAS Number: 141-78-6
Empirical Formula (Hill Notation): C₄H₈O₂
Molecular Weight: 88.11
EC Number: 205-500-4
MDL Number: MFCD00009171
Linear Formula: CH₃COOC₂H₅
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-27227-2.5L-R	2.5 L	$152.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥99.5% (GC)
autoignition temp.	801 °F
bp	76.5-77.5 °C (lit.)
density	0.894-0.898 g/mL at 25 °C
	0.898-0.902 g/mL at 20 °C
	0.902 g/mL at 25 °C (lit.)
expl. lim.	2.2-11.5 %, 38 °F
form	liquid
format	neat
grade	puriss.
impurities	residual solvents, complies
	≤0.003% non-volatile matter
	≤0.005% free acid (as CH₃COOH)
	≤0.01% methyl. comp.(as acetic acid methylester)
	≤0.1% ethanol (GC)
	≤0.1% water (Karl Fischer)
	≤0.2% related subst. (GC)
InChI	1S/C4H8O2/c1-3-6-4(2)5/h3H2,1-2H3
InChI key	XEKOWRVHYACXOJ-UHFFFAOYSA-N
mp	−84 °C (lit.)
quality	meets analytical specification of Ph. Eur., BP, NF
Quality Level	200
refractive index	n20/D 1.371-1.373
	n20/D 1.3720 (lit.)
SMILES string	CCOC(C)=O
suitability	complies for appearance of solution
	complies for reaction against H₂SO₄
	corresponds for chromatography
	passes test for identity (IR)
vapor density	3 (20 °C, vs air)
vapor pressure	73 mmHg ( 20 °C)

Application:

[Determination of 12 prohibited veterinary drug residues in pig urine by ultra high performance liquid chromatography-tandem mass spectrometry]: Ethyl acetate is utilized for sample preparation in this advanced method to detect drug residues in animal samples, emphasizing its role in veterinary pharmaceutical compliance (Wan et al., 2024 ).

Therapeutic effect of Ginkgetin on smoke-induced airway inflammation by down-regulating the c/EBPβ signaling pathway and CCL2 expression: This study explores the anti-inflammatory properties of Ginkgetin, where ethyl acetate is used in the extraction process, highlighting its utility in biomedical research (Tao et al., 2024 ).

Effect of methanol extract of Plectranthus esculentus N.E.Br tuber and its fractions on indices of benign prostatic hyperplasia in Wistar rats: Ethyl acetate is employed in the extraction of bioactive compounds for pharmacological studies, showing its critical role in therapeutic applications (Kanu et al., 2024 ).

Phytochemical evaluation of Ziziphus mucronata and Xysmalobium undulutum towards the discovery and development of anti-malarial drugs: Demonstrates the use of ethyl acetate in phytochemical screenings, contributing to the development of new anti-malarial medications (Buthelezi et al., 2024 ).

The First Records of the In Silico Antiviral and Antibacterial Actions of Molecules Detected in Extracts of Algerian Fir (Abies numidica De Lannoy) Using LC-MS/MS Analysis: This research utilizes ethyl acetate for extracting compounds from plants for antiviral and antibacterial testing, underscoring its importance in the study of natural products (Benouchenne et al., 2024 ).

Other Notes:

The article number 27227-4X2.5L-M will be discontinued. Please order the single bottle 27227-2.5L-M which is physically identical with the same exact specifications.
The article number 27227-4X2.5L-R will be discontinued. Please order the single bottle 27227-2.5L-R which is physically identical with the same exact specifications.

Symbol	GHS02,GHS07
Signal word	Danger
Hazard statements	H225 - H319 - H336
Precautionary statements	P210 - P305 + P351 + P338
Hazard Codes	F,Xi
Risk Statements	11-36-66-67
Safety Statements	16-26-33
RIDADR	UN1173 - class 3 - PG 2 - Ethyl acetate
WGK Germany	WGK 1
Flash Point(F)	24.8 °F
Flash Point(C)	-4 °C

Purity	≥99.5% (GC)
bp	76.5-77.5 °C (lit.)
mp	−84 °C (lit.)
Density	0.898-0.902 g/mL at 20 °C; 0.894-0.898 g/mL at 25 °C; 0.902 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.371-1.373; n20/D 1.3720 (lit.)
UNSPSC	12352108

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