Trifluoroacetic acid
SIGALD/299537 - ≥99%, for protein sequencing
Synonym: TFA
CAS Number: 76-05-1
Empirical Formula (Hill Notation): C2HF3O2
Molecular Weight: 114.02
EC Number: 200-929-3
MDL Number: MFCD00004169
Linear Formula: CF3COOH
Product Type: Chemical
assay | ≥99% |
bp | 72.4 °C (lit.) |
density | 1.489 g/mL at 20 °C (lit.) |
evapn. residue | <0.005% |
form | liquid |
impurities | <0.05% water |
InChI | 1S/C2HF3O2/c3-2(4,5)1(6)7 |
InChI key | DTQVDTLACAAQTR-UHFFFAOYSA |
mp | −15.4 °C (lit.) |
pH | 1 (20 °C, 10 g/L) |
Quality Level | 100 ![]() |
refractive index | n |
SMILES string | OC(C(F)(F)F)=O |
type | for protein sequencing |
vapor density | 3.9 (vs air) |
vapor pressure | 97.5 mmHg ( 20 °C) |
Application: | Trifluoroacetic acid can be used as a solvent in the:• Mass spectrometry for protein identification. • Microwave-irradiated bromination of isoxazoles and pyrazoles with N-bromosuccinimide to synthesize mono-brominated isoxazoles and pyrazoles. • Lewis acid-catalyzed 6-endo-digcyclization of 2-(2-arylethynyl)heteroar • Electrospinning of cellulose acetate to prepare the corresponding nanofibrous membranes. |
General description: | Trifluoroacetic acid is a naturally occurring organic solvent and biodegradable by microbial action. It can also be used as a catalyst for various organic transformations, including solvolysis, rearrangements, reductions, oxidations, and trifluoromethylation. |
Packaging: | 25, 100, 500 g in glass bottle |
Symbol | ![]() ![]() |
Signal word | Danger |
Hazard statements | H314 - H332 - H412 |
Precautionary statements | P261 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
Hazard Codes | C |
Risk Statements | 20-35-52/53 |
Safety Statements | 9-26-27-28-45-61 |
RIDADR | UN 2699 8 / PGI |
WGK Germany | WGK 2 |
Flash Point(F) | No data available |
Flash Point(C) | No data available |
Purity | ≥99% |
bp | 72.4 °C (lit.) |
mp | −15.4 °C (lit.) |
Density | 1.489 g/mL at 20 °C (lit.) |
Refractive Index | n |
UNSPSC | 12352106 |