N,N-Dimethylformamide
SIGALD/319937 - ACS reagent, ≥99.8%
Synonym: DMF; DMF; NSC 5356
CAS Number: 68-12-2
Empirical Formula (Hill Notation): C3H7NO
Molecular Weight: 73.09
EC Number: 200-679-5
MDL Number: MFCD00003284
Linear Formula: HCON(CH3)2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 319937-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 319937-500ML.
| assay | ≥99.8% |
| autoignition temp. | 833 °F |
| bp | 153 °C (lit.) |
| color | clear |
| APHA: ≤15 | |
| density | 0.944 g/mL (lit.) |
| evapn. residue | ≤0.005% |
| expl. lim. | 15.2 % |
| form | liquid |
| grade | ACS reagent |
| impurities | ≤0.0005 meq/g Titr. acid |
| ≤0.003 meq/g Titr. base | |
| ≤0.15% water | |
| InChI | 1S/C3H7NO/c1-4(2)3-5/h3H, |
| InChI key | ZMXDDKWLCZADIW-UHFFFAOYSA |
| mp | −61 °C (lit.) |
| pH | 7 (20 °C, 200 g/L) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | [H]C(=O)N(C)C |
| vapor density | 2.5 (vs air) |
| vapor pressure | 2.7 mmHg ( 20 °C) |
| Application: | DMF can be used as: • A formylating agent for organometallic compounds. • A reactant to prepare Vilsmeier reagent by reacting with phosphorus oxychloride. • A reagent for amination of aryl chlorides in the presence of potassium t-butoxide. • A reducing agent for metal salts to prepare metal colloids. • A catalyst for the regioselective silylation of unprotected carbohydrates. DMF can also be used in the following: • DMF-Phosgene catalytic system is used to prepare alkyl halides from alcohols. • DMF-POCl3 is used to convert acyclic and cyclic enolizable ketones to β-chloro-α, β-unsaturated aldehydes. • DMF-POCl3 is used to synthesize quinoline-3-carbaldehydes from acylanilides. • DMF-SOCl2 combination is used to dehydrate oximes to nitriles. • DMF-Ag2O converts α-bromopropionamides to oxazolidinones. • DMF is frequently used as a solvent in many chemical reactions, which require a high solvency power. |
| Application: | Solvent for many hydrophobic organic compounds. |
| General description: | N, N-Dimethylformamide (DMF) is an organic compound commonly used as a reagent as well as a solvent in organic synthesis. It plays multiple roles in various reactions such as formylating agent, dehydrating agent, reducing agent as well as a catalyst. |
| Packaging: | 1, 6×1, 2.5, 4, 4×4 L in glass bottle |
| Packaging: | 18, 20 L in steel drum |
| Packaging: | 200 L in composite drum |
| Packaging: | 4×4 L in poly bottle |
| Packaging: | 500 mL in glass bottle |
| Packaging: | 56 L in Pure-Pac™ 1 |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H226 - H312 + H332 - H319 - H360D |
| Precautionary statements | P210 - P280 - P303 + P361 + P353 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-20/21-36 |
| Safety Statements | 53-45 |
| RIDADR | UN 2265 3 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 135.5 °F - closed cup |
| Flash Point(C) | 57.5 °C - closed cup |
| Purity | ≥99.8% |
| bp | 153 °C (lit.) |
| mp | −61 °C (lit.) |
| Density | 0.944 g/mL (lit.) |
| Refractive Index | n |
| UNSPSC | 12352111 |