Dichloromethane

SIGALD/320269 - ACS reagent, ≥99.5%, contains 40-150 ppm amylene as stabilizer

Synonym: methylene chloride; Methylene chloride

CAS Number: 75-09-2
Empirical Formula (Hill Notation): CH₂Cl₂
Molecular Weight: 84.93
EC Number: 200-838-9
MDL Number: MFCD00000881
Linear Formula: CH₂Cl₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-320269-1L	1 L	$97.30 1/EA	Add To Favorites
45-320269-4L	4 L	$218.00 1/EA	Add To Favorites
45-320269-4X4L	4 L	$755.00 4/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	suitable for EPA 1613
assay	≥99.5%
autoignition temp.	1223 °F
bp	39.8-40 °C (lit.)
color	APHA: ≤10
	clear
contains	40-150 ppm amylene as stabilizer
density	1.325 g/mL at 25 °C (lit.)
evapn. residue	≤0.002%
expl. lim.	22 %
form	liquid
grade	ACS reagent
impurities	Free halogens, passes test
	≤0.0003 meq/g Titr. acid
	≤0.02% water
InChI	1S/CH2Cl2/c2-1-3/h1H2
InChI key	YMWUJEATGCHHMB-UHFFFAOYSA-N
mp	−95 °C (lit.)
Quality Level	200
refractive index	n20/D 1.424 (lit.)
SMILES string	ClCCl
vapor density	2.9 (vs air)
vapor pressure	24.45 psi ( 55 °C)
	6.83 psi ( 20 °C)

Application:	Rapid and Comprehensive Analysis of 41 Harmful Substances in Multi-Matrix Products by Gas Chromatography-Mass Spectrometry Using Matrix-Matching Calibration Strategy.: This research uses gas chromatography-mass spectrometry (GC-MS) to analyze harmful substances across various matrices. Dichloromethane is employed as a solvent in the preparation phase, highlighting its application in ensuring accurate and efficient analytical results (Wang Y et al., 2024 ). Brunonianines D-F, three new C19-diterpenoid alkaloids from the Delphinium brunonianum, with therapeutic effect on ovarian cancer in vitro and in vivo.: This study identifies new alkaloids with potential anti-cancer properties, where dichloromethane is utilized in the extraction and isolation processes. Its effectiveness in separating and preserving delicate compounds is critical for their pharmacological evaluation (Li Q et al., 2024 ). LC-HRMS and GC-MS Profiling of Urine Free Cortisol, Cortisone, 6Β-, and 18-Hydroxycortisol for the Evaluation of Glucocorticoid and Mineralocorticoid Disorders.: Utilizes LC-HRMS and GC-MS to profile hormones in urine, with dichloromethane being crucial in the extraction process. This method ensures precision and sensitivity in hormone measurement, essential for diagnosing endocrine disorders (Casals G et al., 2024 ). Determination of vancomycin and meropenem in serum and synovial fluid of patients with prosthetic joint infections using UPLC-MS/MS.: Features a method to measure antibiotics in biological fluids, where dichloromethane is used to prepare samples. This study underscores the solvent′s role in achieving high resolution and detection limits in clinical diagnostics (He J et al., 2024 ).
Features and Benefits:	ACS solvents meet or exceed the high standards of the American Chemical Society (ACS) ,with test specifications that are specialized to every compound. According to the American Chemical Society, ACS reagent grade implies that it is a substance of sufficient purity to be used in most chemical analyses or reactions.
Packaging:	1, 4, 4×4 L in PVC-coated bottle

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H315 - H319 - H336 - H351
Precautionary statements	P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313
Hazard Codes	Xn
Risk Statements	36/37/38-40-67
Safety Statements	3-9-26-36/37-60
RIDADR	UN 1593 6.1 / PGIII
WGK Germany	WGK 2
Flash Point(F)	does not flash
Flash Point(C)	does not flash

Purity	≥99.5%
bp	39.8-40 °C (lit.)
mp	−95 °C (lit.)
Density	1.325 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.424 (lit.)
UNSPSC	12352101

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