Chloroform
SIGALD/32211 - puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)
Synonym: Methylidyne trichloride; Trichloromethane
CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
EC Number: 200-663-8
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
agency | reag. ISO |
reag. Ph. Eur. | |
USP/NF | |
anion traces | chloride (Cl-): ≤1 mg/kg |
assay | 99.0-99.4% (GC) |
bp | 60.5-61.5 °C (lit.) |
cation traces | Al: ≤0.5 mg/kg |
B: ≤0.02 mg/kg | |
Ba: ≤0.1 mg/kg | |
Ca: ≤0.5 mg/kg | |
Cd: ≤0.05 mg/kg | |
Co: ≤0.02 mg/kg | |
Cr: ≤0.02 mg/kg | |
Cu: ≤0.02 mg/kg | |
Fe: ≤0.1 mg/kg | |
Mg: ≤0.1 mg/kg | |
Mn: ≤0.02 mg/kg | |
Ni: ≤0.02 mg/kg | |
Pb: ≤0.05 mg/kg | |
Sn: ≤0.1 mg/kg | |
Zn: ≤0.1 mg/kg | |
contains | ~1% ethanol as stabilizer |
density | 1.476-1.483 g/mL at 20 °C |
1.492 g/mL at 25 °C (lit.) | |
form | liquid |
grade | puriss. p.a. |
impurities | ≤0.00001% free chlorine (Cl) |
≤0.00005% free acid (as HCl) | |
≤0.0005% non-volatile matter | |
≤0.005% aldehydes and ketones (as CH3COCH3) | |
≤0.005% carbonyl compounds (as CO) | |
≤0.01% tetrachloroethene (GC) | |
≤0.01% tetrachloromethane (GC) | |
≤0.01% trichloroethene (GC) | |
≤0.01% water (Karl Fischer) | |
≤0.03% dichloromethane (GC) | |
0.6-1.0% ethanol (GC) | |
InChI | 1S/CHCl3/c2-1(3)4/h1H |
InChI key | HEDRZPFGACZZDS-UHFFFAOYSA |
mp | −63 °C (lit.) |
Quality Level | 200 |
refractive index | n |
SMILES string | ClC(Cl)Cl |
suitability | complies for appearance |
complies for reaction against H2SO4 | |
complies for suitability of determ. w. dithizone | |
technique(s) | RNA extraction: suitable |
vapor density | 4.1 (vs air) |
vapor pressure | 160 mmHg ( 20 °C) |
Application: | Chloroform may be employed as a solvent for the following studies: • Extraction of RNA from plant cells. • Preparation of dioleoylphosphatidylcholi • Dissolution of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC). It may be employed in a rapid quantitative method for the release of periplasmic proteins from bacterial strains. |
Application: | Chloroform may be used as a solvent to enhance the enantioselectivity of secondary alcohols formed by the borohydride reduction of carbonyl compounds in the presence of optically active ketoiminatocobalt complexes. |
General description: | Chloroform, a halogenated hydrocarbon, is widely employed as a solvent. Its photochemical degradation has been investigated in the presence of TiO2 aqueous suspensions (wavelength range of 310-380nm). |
Other Notes: | For information on chloroform miscibility, please visit the following link: Chloroform Miscibility/Immiscibility Table |
Other Notes: | The article number 32211-4X2.5L will be discontinued. Please order the single bottle 32211-2.5L which is physically identical with the same exact specifications. The article number 32211-4X2.5L-M will be discontinued. Please order the single bottle 32211-2.5L-M which is physically identical with the same exact specifications. The article number 32211-6X1L will be discontinued. Please order the single bottle 32211-1L which is physically identical with the same exact specifications. The article number 32211-6X1L-M will be discontinued. Please order the single bottle 32211-1L-M which is physically identical with the same exact specifications. |
Symbol | GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
Precautionary statements | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
Hazard Codes | Xn |
Risk Statements | 63-20/22-36/38-40-48/20/22 |
Safety Statements | 26-36/37 |
RIDADR | UN 1888 6.1 / PGIII |
WGK Germany | WGK 3 |
Flash Point(F) | does not flash |
Flash Point(C) | does not flash |
Purity | 99.0-99.4% (GC) |
bp | 60.5-61.5 °C (lit.) |
mp | −63 °C (lit.) |
Density | 1.476-1.483 g/mL at 20 °C; 1.492 g/mL at 25 °C (lit.) |
Refractive Index | n |
UNSPSC | 12191502 |