Chloroform
SIGALD/32211 - puriss. p.a., reag. ISO, reag. Ph. Eur., 99.0-99.4% (GC)
Synonym: Methylidyne trichloride; Trichloromethane
CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
EC Number: 200-663-8
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
| agency | reag. ISO |
| reag. Ph. Eur. | |
| USP/NF | |
| anion traces | chloride (Cl-): ≤1 mg/kg |
| assay | 99.0-99.4% (GC) |
| bp | 60.5-61.5 °C (lit.) |
| cation traces | Al: ≤0.5 mg/kg |
| B: ≤0.02 mg/kg | |
| Ba: ≤0.1 mg/kg | |
| Ca: ≤0.5 mg/kg | |
| Cd: ≤0.05 mg/kg | |
| Co: ≤0.02 mg/kg | |
| Cr: ≤0.02 mg/kg | |
| Cu: ≤0.02 mg/kg | |
| Fe: ≤0.1 mg/kg | |
| Mg: ≤0.1 mg/kg | |
| Mn: ≤0.02 mg/kg | |
| Ni: ≤0.02 mg/kg | |
| Pb: ≤0.05 mg/kg | |
| Sn: ≤0.1 mg/kg | |
| Zn: ≤0.1 mg/kg | |
| contains | ~1% ethanol as stabilizer |
| density | 1.476-1.483 g/mL at 20 °C |
| 1.492 g/mL at 25 °C (lit.) | |
| form | liquid |
| grade | puriss. p.a. |
| impurities | ≤0.00001% free chlorine (Cl) |
| ≤0.00005% free acid (as HCl) | |
| ≤0.0005% non-volatile matter | |
| ≤0.005% aldehydes and ketones (as CH3COCH3) | |
| ≤0.005% carbonyl compounds (as CO) | |
| ≤0.01% tetrachloroethene (GC) | |
| ≤0.01% tetrachloromethane (GC) | |
| ≤0.01% trichloroethene (GC) | |
| ≤0.01% water (Karl Fischer) | |
| ≤0.03% dichloromethane (GC) | |
| 0.6-1.0% ethanol (GC) | |
| InChI | 1S/CHCl3/c2-1(3)4/h1H |
| InChI key | HEDRZPFGACZZDS-UHFFFAOYSA |
| mp | −63 °C (lit.) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | ClC(Cl)Cl |
| suitability | complies for appearance |
| complies for reaction against H2SO4 | |
| complies for suitability of determ. w. dithizone | |
| technique(s) | RNA extraction: suitable |
| vapor density | 4.1 (vs air) |
| vapor pressure | 160 mmHg ( 20 °C) |
| Application: | Chloroform may be employed as a solvent for the following studies: • Extraction of RNA from plant cells. • Preparation of dioleoylphosphatidylcholi • Dissolution of 1,2-distearoyl-sn-glycero-3-phosphocholine (DSPC). It may be employed in a rapid quantitative method for the release of periplasmic proteins from bacterial strains. |
| Application: | Chloroform may be used as a solvent to enhance the enantioselectivity of secondary alcohols formed by the borohydride reduction of carbonyl compounds in the presence of optically active ketoiminatocobalt complexes. |
| General description: | Chloroform, a halogenated hydrocarbon, is widely employed as a solvent. Its photochemical degradation has been investigated in the presence of TiO2 aqueous suspensions (wavelength range of 310-380nm). |
| Other Notes: | For information on chloroform miscibility, please visit the following link: Chloroform Miscibility/Immiscibility Table |
| Other Notes: | The article number 32211-4X2.5L will be discontinued. Please order the single bottle 32211-2.5L which is physically identical with the same exact specifications. The article number 32211-4X2.5L-M will be discontinued. Please order the single bottle 32211-2.5L-M which is physically identical with the same exact specifications. The article number 32211-6X1L will be discontinued. Please order the single bottle 32211-1L which is physically identical with the same exact specifications. The article number 32211-6X1L-M will be discontinued. Please order the single bottle 32211-1L-M which is physically identical with the same exact specifications. |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412 |
| Precautionary statements | P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 63-20/22-36/38-40-48/20/22 |
| Safety Statements | 26-36/37 |
| RIDADR | UN 1888 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| Purity | 99.0-99.4% (GC) |
| bp | 60.5-61.5 °C (lit.) |
| mp | −63 °C (lit.) |
| Density | 1.476-1.483 g/mL at 20 °C; 1.492 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12191502 |