Hydrogen chloride solution
SIGALD/345547 - 4.0 M in dioxane
CAS Number: 7647-01-0
Empirical Formula (Hill Notation): HCl
Molecular Weight: 36.46
MDL Number: MFCD00011324
Linear Formula: HCl
Product Type: Chemical
4×100 Slip-cover Can
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
Photo is meant to be representative of product you will receive if ordered. Additional information is printed on actual labels and package types are subject to change.
| concentration | 3.80-4.40 M (by NaOH, titration) |
| 4.0 M in dioxane | |
| density | 1.05 g/mL at 25 °C |
| form | liquid |
| InChI | 1S/ClH/h1H |
| InChI key | VEXZGXHMUGYJMC-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | Cl |
| Application: | Hydrogen chloride solution (4.0 M in dioxane) can be used as: • A reagent for the deprotection of the N-Boc protecting group from various heterocyclic derivatives. • A reagent for the deprotection of polymer protecting groups. For instance, deprotection of benzyl ether-protected polymer. • A polymerization initiator in combination with ZnCl2 in the synthesis of formyl terminated poly(ethyl vinyl ether) from ethyl vinyl ether (EVE). |
| General description: | Hydrogen chloride solution contains 4.0 M hydrogen chloride in 1,4-dioxane as the solvent. It is commonly used as a deprotection reagent during the deprotection of the tert-butoxycarbonyl (Boc) group of various amino acids and peptides. Additionally, it serves as a reagent in various organic synthesis reactions, including the synthesis of N-9-Fluorenylmethoxycarbon |
| Packaging: | 100, 4×100, 800 mL in Sure/Seal™ |
| Packaging: | 2 L in Sure/Seal™ |
| Symbol |     GHS02,GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H290 - H315 - H319 - H335 - H351 |
| Precautionary statements | P202 - P210 - P233 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | F,Xn |
| Risk Statements | 11-19-36/37/38-40 |
| Safety Statements | 9-16-26-33-36/37-60 |
| RIDADR | UN 2924 8(3) / PGII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 62.6 °F - closed cup |
| Flash Point(C) | 17 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Density | 1.05 g/mL at 25 °C |
| UNSPSC | 12352301 |