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Chloroform

SIGALD/366927 - suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Synonym: Methylidyne trichloride; Trichloromethane

CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl3
Molecular Weight: 119.38
MDL Number: MFCD00000826
Linear Formula: CHCl3
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-366927-100ML 100 mL
 $94.30
1/EA		 Add To Favorites
45-366927-1L 1 L
 $135.00
1/EA		 Add To Favorites
45-366927-4L 4 L
 $326.00
1/EA		 Add To Favorites
45-366927-4X4L 4 L
 $448.84
4/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 366927-100ML.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 366927-1L.

 

λ H2O reference
assay ≥99.8%
bp 60.5-61.5 °C (lit.)
cation traces Pb: ≤0.05 ppm
color APHA: ≤10
contains 0.5-1.0% ethanol as stabilizer
density 1.48 g/mL at 25 °C
  1.492 g/mL at 25 °C (lit.)
evapn. residue <0.0003%
form liquid
grade HPLC grade
impurities Acetone and aldehyde, passes test
  Acid and chloride, passes test
  Free chlorine (Cl), passes test
  H2SO4, passes test (darkened)
  ≤0.01% water
InChI 1S/CHCl3/c2-1(3)4/h1H
InChI key HEDRZPFGACZZDS-UHFFFAOYSA-N
mp −63 °C (lit.)
purified by glass distillation
Quality Level 100 
refractive index n20/D 1.445 (lit.)
SMILES string ClC(Cl)Cl
storage temp. room temp
suitability passes test for HPLC
technique(s) HPLC: suitable
UV absorption λ: 245 nm Amax: 1.00
  λ: 255 nm Amax: 0.15
  λ: 260 nm Amax: 0.15
  λ: 270 nm Amax: 0.02
  λ: 290 nm Amax: 0.01
  λ: 400 nm Amax: 0.01
vapor density 4.1 (vs air)
vapor pressure 160 mmHg ( 20 °C)
Application:

  • Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024 ).

  • Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024 ).

  • Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024 ).

  • Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024 ).
Other Notes: Discover LiChropur reagents ideal for HPLC  or LC-MS  analysis
Packaging: 1, 4, 4×4 L in glass bottle
Packaging: 100 mL in glass bottle
Packaging: M-Bottle for Solvents
As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before.
See all the new features here! 
Purity ≥99.8%
bp 60.5-61.5 °C (lit.)
mp −63 °C (lit.)
Density 1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
Refractive Index n20/D 1.445 (lit.)
Storage Temp. room temp
UNSPSC 12190000

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