Chloroform

SIGALD/366927 - suitable for HPLC, ≥99.8%, contains 0.5-1.0% ethanol as stabilizer

Synonym: Methylidyne trichloride; Trichloromethane

CAS Number: 67-66-3
Empirical Formula (Hill Notation): CHCl₃
Molecular Weight: 119.38
MDL Number: MFCD00000826
Linear Formula: CHCl₃
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-366927-100ML	100 mL	$85.70 1/EA	Add To Favorites
45-366927-1L	1 L	$122.00 1/EA	Add To Favorites
45-366927-4L	4 L	$296.00 1/EA	Add To Favorites
45-366927-4X4L	4 L	$400.07 4/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 366927-100ML.

Properties
Descriptions
Safety Info.
Basic Data

λ	H₂O reference
assay	≥99.8%
bp	60.5-61.5 °C (lit.)
cation traces	Pb: ≤0.05 ppm
color	APHA: ≤10
contains	0.5-1.0% ethanol as stabilizer
density	1.48 g/mL at 25 °C
	1.492 g/mL at 25 °C (lit.)
evapn. residue	<0.0003%
form	liquid
impurities	Acetone and aldehyde, passes test
	Acid and chloride, passes test
	Free chlorine (Cl), passes test
	H₂SO₄, passes test (darkened)
	≤0.01% water
InChI	1S/CHCl3/c2-1(3)4/h1H
InChI key	HEDRZPFGACZZDS-UHFFFAOYSA-N
mp	−63 °C (lit.)
purified by	glass distillation
Quality Level	100
refractive index	n20/D 1.445 (lit.)
SMILES string	ClC(Cl)Cl
storage temp.	room temp
suitability	passes test for HPLC
technique(s)	HPLC: suitable
UV absorption	λ: 245 nm A_max: 1.00
	λ: 255 nm A_max: 0.15
	λ: 260 nm A_max: 0.15
	λ: 270 nm A_max: 0.02
	λ: 290 nm A_max: 0.01
	λ: 400 nm A_max: 0.01
vapor density	4.1 (vs air)
vapor pressure	160 mmHg ( 20 °C)

Application:	Novel Approaches for the Analysis and Isolation of Benzylisoquinoline Alkaloids in Chelidonium majus.: This study presents innovative methodologies using chloroform in the extraction and analysis processes, highlighting advances in alkaloid chemistry (Ganzera et al., 2024 ). Antioxidant, anti-amylase, anti-lipase, and efficiency of Satureja fatty acid on the anti-inflammatory parameters in lipopolysaccharide-stimulated macrophage through Nrf2/NF-kB/NADH oxidase pathway.: Although primarily focused on biological assays, this paper includes essential methodologies employing chloroform for the extraction and purification of biochemical compounds (Saharkhiz MJ et al., 2024 ). Recent additions and access to a multidimensional lipidomic database containing liquid chromatography, ion mobility spectrometry, and tandem mass spectrometry information.: Chloroform is utilized as a key solvent in the extraction and analysis processes within lipidomics, demonstrating its critical role in modern analytical techniques (Baker ES et al., 2024 ). Preparation and optimization of dummy molecularly imprinted polymer-based solid-phase extraction system for selective enrichment of p-toluene sulfonate esters genotoxic impurities.: The study includes the use of chloroform in the preparation of polymers for advanced chromatographic applications, illustrating its versatility in analytical methodologies (Shan G et al., 2024 ).
Packaging:	1, 4, 4×4 L in glass bottle
Packaging:	100 mL in glass bottle
Recommended products:	Discover LiChropur reagents ideal for HPLC or LC-MS analysis

Symbol	GHS06,GHS08
Signal word	Danger
Hazard statements	H302 - H315 - H319 - H331 - H336 - H351 - H361d - H372 - H412
Precautionary statements	P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
Hazard Codes	Xn
Risk Statements	63-20/22-36/38-40-48/20/22
Safety Statements	26-36/37
RIDADR	UN 1888 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	does not flash
Flash Point(C)	does not flash

Purity	≥99.8%
bp	60.5-61.5 °C (lit.)
mp	−63 °C (lit.)
Density	1.48 g/mL at 25 °C; 1.492 g/mL at 25 °C (lit.)
Refractive Index	n20/D 1.445 (lit.)
Storage Temp.	room temp
UNSPSC	12190000

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