Periodic acid
SIGALD/375810 - ACS reagent, 99%
CAS Number: 10450-60-9
Empirical Formula (Hill Notation): H5IO6
Molecular Weight: 227.94
EC Number: 233-937-0
MDL Number: MFCD00011344
Linear Formula: H5IO6
Product Type: Chemical
| anion traces | sulfate (SO42-): ≤0.01% |
| application(s) | histology |
| assay | 99% |
| 99.0-101.0% (ACS specification) | |
| cation traces | Fe: ≤0.003% |
| heavy metals: ≤0.005% | |
| form | powder or crystals |
| grade | ACS reagent |
| ign. residue | ≤0.01% |
| impurities | ≤0.01% insolubles |
| ≤0.01% other halogens | |
| InChI | 1S/H5IO6/c2-1(3,4,5,6)7/h |
| InChI key | TWLXDPFBEPBAQB-UHFFFAOYSA |
| mp | 122 °C (lit.) |
| Quality Level | 200  |
| reaction suitability | reaction type: C-H Activation |
| reagent type: catalyst | |
| reagent type: oxidant | |
| SMILES string | OI(O)(O)(O)(O)=O |
| solubility | water: soluble |
| Application: | Periodic acid may be used in the following reactions: • Oxidation of alcohols to ketones and aldehydes. • Oxidation hydroxylamine derivatives. • Oxidation of arenes to quinones. • Deprotection of the dithio- and oxathio-derivatives. • Oxidative degradation of epoxidized natural rubber (ENR). • Oxidation of urazoles and bis-urazoles to triazolinediones. • Oxidative cleavage of glucosazone. |
| General description: | Periodic acid is an inorganic acid commonly used as an oxidizing agent. Periodic acid oxidation is one of the steps in the periodate-resorcinol assay, used in the determination of sialic acid. Periodic acid reacts with 1,2 glycol linkage of carbohydrates to form aldehydes which can be stained by Schiff’s reagent. Therefore periodic-acid-Schiff′s reagent (PAS) is used in histochemistry to determine carbohydrates in tissue sections. |
| Packaging: | 25, 100 g in glass bottle |
| Symbol |     GHS03,GHS05,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H271 - H314 - H372 - H410 |
| Precautionary statements | P210 - P260 - P273 - P280 - P303 + P361 + P353 - P305 + P351 + P338 |
| Hazard Codes | O,C |
| Risk Statements | 8-34 |
| Safety Statements | 17-26-36/37/39-45 |
| RIDADR | UN 3085 8(5.1) / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99%; 99.0-101.0% (ACS specification) |
| mp | 122 °C (lit.) |
| UNSPSC | 12352106 |