Hydrogen chloride solution
SIGALD/455180 - 2.0 M in diethyl ether
CAS Number: 7647-01-0
Empirical Formula (Hill Notation): HCl
Molecular Weight: 36.46
MDL Number: MFCD00011324
Linear Formula: HCl
Product Type: Chemical
| bp | 34.6 °C |
| concentration | 1.90-2.20 M (with NaOH, titration) |
| 2.0 M in diethyl ether | |
| density | 0.747 g/mL at 25 °C |
| form | liquid |
| InChI | 1S/ClH/h1H |
| InChI key | VEXZGXHMUGYJMC-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | Cl |
| storage temp. | 2-8°C |
| Application: | Hydrogen chloride solution can be used as a reagent to synthesize:• Cyanohydrin alkyl ethers via chiral Bronsted acid-mediated hydrocyanation of vinyl ethers with silyl cyanides. • N, N-Dimethylaniline hydrochloride salts via Pd-catalyzed Buchwald-Hartwig amination of aryl triflates with dimethylamines. It can also be used as a catalyst for the amidation of carboxylic acids with amines to synthesize amides. |
| General description: | Hydrogen chloride solution contains 2M hydrogen chloride in diethyl ether as the solvent. It is a strong acid and highly corrosive in nature and is commonly used in the selective cleavage of the protecting groups 2,4,6-trimethoxyphenyl from the respective (2,4,6-trimethoxyphenyl)s |
| Packaging: | 100, 4×100, 800 mL in Sure/Seal™ |
| Symbol |    GHS02,GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H224 - H290 - H302 - H331 - H336 - H412 |
| Precautionary statements | P210 - P233 - P273 - P301 + P312 - P304 + P340 + P311 - P403 + P233 |
| Hazard Codes | F+,C |
| Risk Statements | 12-19-20/22-35 |
| Safety Statements | 3-16-26-33-36/37/39-45 |
| RIDADR | UN 2924 8(3) / PGI |
| WGK Germany | WGK 1 |
| Flash Point(F) | -29.2 °F - closed cup |
| Flash Point(C) | -34 °C - closed cup |
| Supplemental Hazard Statements | EUH019 - EUH066 |
| bp | 34.6 °C |
| Density | 0.747 g/mL at 25 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352301 |