Hydrogen chloride solution
SIGALD/455180 - 2.0 M in diethyl ether
CAS Number: 7647-01-0
Empirical Formula (Hill Notation): HCl
Molecular Weight: 36.46
MDL Number: MFCD00011324
Linear Formula: HCl
Product Type: Chemical
bp | 34.6 °C |
concentration | 1.90-2.20 M (with NaOH, titration) |
2.0 M in diethyl ether | |
density | 0.747 g/mL at 25 °C |
form | liquid |
InChI | 1S/ClH/h1H |
InChI key | VEXZGXHMUGYJMC-UHFFFAOYSA |
Quality Level | 100 |
SMILES string | Cl |
storage temp. | 2-8°C |
Application: | Hydrogen chloride solution can be used as a reagent to synthesize:• Cyanohydrin alkyl ethers via chiral Bronsted acid-mediated hydrocyanation of vinyl ethers with silyl cyanides. • N, N-Dimethylaniline hydrochloride salts via Pd-catalyzed Buchwald-Hartwig amination of aryl triflates with dimethylamines. It can also be used as a catalyst for the amidation of carboxylic acids with amines to synthesize amides. |
General description: | Hydrogen chloride solution contains 2M hydrogen chloride in diethyl ether as the solvent. It is a strong acid and highly corrosive in nature and is commonly used in the selective cleavage of the protecting groups 2,4,6-trimethoxyphenyl from the respective (2,4,6-trimethoxyphenyl)s |
Packaging: | 100, 4×100, 800 mL in Sure/Seal™ |
Symbol | GHS02,GHS05,GHS06 |
Signal word | Danger |
Hazard statements | H224 - H290 - H302 - H331 - H336 - H412 |
Precautionary statements | P210 - P233 - P273 - P301 + P312 - P304 + P340 + P311 - P403 + P233 |
Hazard Codes | F+,C |
Risk Statements | 12-19-20/22-35 |
Safety Statements | 3-16-26-33-36/37/39-45 |
RIDADR | UN 2924 8(3) / PGI |
WGK Germany | WGK 1 |
Flash Point(F) | -29.2 °F - closed cup |
Flash Point(C) | -34 °C - closed cup |
Supplemental Hazard Statements | EUH019 - EUH066 |
bp | 34.6 °C |
Density | 0.747 g/mL at 25 °C |
Storage Temp. | 2-8°C |
UNSPSC | 12352301 |