Methyl acetate
SIGALD/45999 - suitable for HPLC, ≥99.8%
CAS Number: 79-20-9
Empirical Formula (Hill Notation): C3H6O2
Molecular Weight: 74.08
EC Number: 201-185-2
MDL Number: MFCD00008711
Linear Formula: CH3COOCH3
Product Type: Chemical
| λ | 1 cm path, H2O reference |
| assay | ≥99.8% |
| ≥99.8% (GC) | |
| autoignition temp. | 936 °F |
| bp | 57-58 °C (lit.) |
| density | 0.934 g/mL at 25 °C |
| evapn. residue | ≤0.001% |
| expl. lim. | 16 % |
| form | liquid |
| impurities | ≤0.05% water |
| InChI | 1S/C3H6O2/c1-3(4)5-2/h1-2 |
| InChI key | KXKVLQRXCPHEJC-UHFFFAOYSA |
| mp | −98 °C (lit.) |
| Quality Level | 100  |
| refractive index | n |
| n |
|
| shelf life | limited shelf life, expiry date on the label |
| SMILES string | COC(C)=O |
| solvent strength ε (Al2O3) | 0.60 |
| technique(s) | HPLC: suitable |
| UV absorption | λ: 255 nm Amax: 1.0 |
| λ: 275 nm Amax: 0.1 | |
| λ: 300 nm Amax: 0.01 | |
| vapor density | 2.55 (vs air) |
| vapor pressure | 165 mmHg ( 20 °C) |
| Application: | • Agglomeration of celecoxib by quasi-emulsion solvent diffusion method without stabilizer: effect of good solvent.: This research explored the agglomeration of celecoxib using the quasi-emulsion solvent diffusion method, highlighting the role of methyl acetate as a good solvent to improve particle size and distribution without the need for stabilizers (Maghsoodi & Nokhodchi, 2018  ).• Formulation and in vitro evaluation of ketoprofen in palm oil esters nanoemulsion for topical delivery.: The formulation and evaluation of ketoprofen in a nanoemulsion system for topical delivery were examined, with methyl acetate used as a solvent to enhance solubility and stability of the active ingredient (Sakeena et al., 2010 ).• Preparation of surfactant-free nanoparticles of methacrylic acid copolymers used for film coating.: This paper presented a method for preparing surfactant-free nanoparticles using methyl acetate as a solvent, emphasizing its role in the formation of uniform nanoparticle dispersions for coating applications (Nguyen et al., 2006 ). |
| Other Notes: | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H336 |
| Precautionary statements | P210 - P233 - P240 - P241 - P242 - P305 + P351 + P338 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-36-66-67 |
| Safety Statements | 16-26-29-33 |
| RIDADR | UN1231 - class 3 - PG 2 - Methyl acetate |
| WGK Germany | WGK 1 |
| Flash Point(F) | 8.6 °F - closed cup |
| Flash Point(C) | -13 °C - closed cup |
| Supplemental Hazard Statements | EUH066 |
| Purity | ≥99.8% (GC); ≥99.8% |
| bp | 57-58 °C (lit.) |
| mp | −98 °C (lit.) |
| Density | 0.934 g/mL at 25 °C |
| Refractive Index | n |
| UNSPSC | 12190000 |