1-Methyl-2-pyrrolidinone
SIGALD/494496 - biotech. grade, ≥99.7%
Synonym: 1-
CAS Number: 872-50-4
Empirical Formula (Hill Notation): C5H9NO
Molecular Weight: 99.13
EC Number: 212-828-1
MDL Number: MFCD00003193
Linear Formula: C5H9NO
Product Type: Chemical
| λ | H2O reference |
| application(s) | peptide synthesis |
| assay | ≥99.7% |
| autoignition temp. | 518 °F |
| bp | 202 °C (lit.) |
| 81-82 °C/10 mmHg (lit.) | |
| color | APHA: ≤20 |
| density | 1.028 g/mL at 25 °C (lit.) |
| expl. lim. | 9.5 % |
| form | liquid |
| grade | biotech. grade |
| impurities | ≤0.005% water |
| ≤0.01% free amines (CH3NH2) | |
| InChI | 1S/C5H9NO/c1-6-4-2-3-5(6) |
| InChI key | SECXISVLQFMRJM-UHFFFAOYSA |
| mp | −24 °C (lit.) |
| pH | 7.7-10.0 (20 °C, 100 g/L) |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | CN1CCCC1=O |
| solubility | acetone: miscible(lit.) |
| alcohol: miscible(lit.) | |
| chloroform: miscible(lit.) | |
| ethyl acetate: miscible(lit.) | |
| water: miscible(lit.) | |
| UV absorption | λ: 285 nm Amax: 1.00 |
| λ: 300 nm Amax: 0.50 | |
| λ: 325 nm Amax: 0.10 | |
| λ: 350-400 nm Amax: 0.01 | |
| vapor density | 3.4 (vs air) |
| vapor pressure | 0.29 mmHg ( 20 °C) |
| 0.99 mmHg ( 40 °C) |
| General description: | N-Methyl-2-pyrrolidinone (N-methylpyrrolidone, NMP) is a polar cyclic organic solvent. A study on the impact of NMP on Saccharomyces cerevisiae revealed that it induced aneuploidy. Characteristic properties of NMP include low viscosity, excellent dissolving power and enhanced demulsifying property. It is a better alternative to phenol in selectively treating lube feedstock. The behavior of fullerene-C60 in NMP solution has been examined based on electronic absorption and photoluminescence spectral data. A solution of sodium borohydride (NaBH4) in NMP showed increased reactivity towards debromination of alkyl bromide. The enhanced selectivity of NMP-ethylene glycol solvent mixture for aromatic hydrocarbon extraction has been analyzed by gas chromatography. |
| General description: | Our biotech solvents offer exceptional quality for reliable RNA extraction, ensuring optimal laboratory performance. With low water content and minimal residue, give clean UV spectra to minimize contamination. • High-Quality Biotech Solvents: Designed for optimal laboratory performance with low water content and minimal residues. • Ideal for RNA Extraction: Essential for genetic testing and research applications like PCR. • Ensures Integrity of Genetic Material: Promotes reliable and reproducible results. • Industry Compliant: Suitable for both academic and commercial laboratories, enhancing research efficiency. |
| Packaging: | 1, 2, 4×2 L in Sure/Seal™ |
| Packaging: | View returnable container options . |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H335 - H360FD |
| Precautionary statements | P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-36/37/38 |
| Safety Statements | 53-45 |
| WGK Germany | WGK 3 |
| Flash Point(F) | 195.8 °F - Pensky-Martens c |
| Flash Point(C) | 91 °C - Pensky-Martens clos |
| Purity | ≥99.7% |
| bp | 202 °C (lit.); 81-82 °C/10 mmHg (lit.) |
| mp | −24 °C (lit.) |
| Density | 1.028 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352005 |