N,N-Diisopropylethylamine
SIGALD/496219 - 99.5%, biotech. grade
Synonym: N-
CAS Number: 7087-68-5
Empirical Formula (Hill Notation): C8H19N
Molecular Weight: 129.24
EC Number: 230-392-0
MDL Number: MFCD00008868
Linear Formula: [(CH3)2CH]2NC2H5
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | 99.5% |
| bp | 127 °C (lit.) |
| color | APHA: <20 |
| density | 0.742 g/mL at 25 °C (lit.) |
| form | liquid |
| grade | biotech. grade |
| impurities | <0.050% water |
| InChI | 1S/C8H19N/c1-6-9(7(2)3)8( |
| InChI key | JGFZNNIVVJXRND-UHFFFAOYSA |
| mp | <−50 °C (lit.) |
| pH | 12.3 (20 °C) |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | CCN(C(C)C)C(C)C |
| solubility | water: soluble 4.01 g/L at 20 °C |
| vapor pressure | 31 mmHg ( 37.7 °C) |
| Application: | N, N-Diisopropylethylamine can be used as a base: • In the palladium (0)-catalyzed alkoxy carbonylation of allyl phosphates and acetate. • In the selective enolate formation along with boryl triflates. • In the C–N coupling of aryl halides with nitroarenes in the presence of nickel catalyst. |
| Application: | N,N-Diisopropylethylamine may be used in the synthesis of mannosylated ovalbumin peptides. |
| General description: | N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts. |
| General description: | N, N-Diisopropylethylamine is a hindered non-nucleophilic amine base used in alkylation, aldol-like reactions, eliminations, and selective generation of enolates. It is widely used as a proton scavenger in organic synthesis. Due to its less nucleophilic nature, it produces less byproducts. |
| Packaging: | 100, 500 mL in Sure/Seal™ |
| Packaging: | 2 L in Sure/Seal™ |
| Symbol |    GHS02,GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H225 - H302 - H318 - H331 - H335 |
| Precautionary statements | P210 - P280 - P301 + P312 + P330 - P304 + P340 + P311 - P305 + P351 + P338 + P310 |
| Hazard Codes | F,T |
| Risk Statements | 11-20/22-37/38-41 |
| Safety Statements | 9-16-26-36/37/39-45 |
| RIDADR | UN 3384 3(6.1) / PGI |
| WGK Germany | WGK 2 |
| Flash Point(F) | 49.1 °F |
| Flash Point(C) | 9.5 °C |
| Purity | 99.5% |
| bp | 127 °C (lit.) |
| mp | <−50 °C (lit.) |
| Density | 0.742 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352116 |