Dichloromethane
SIGALD/650463 - HPLC Plus, for HPLC, GC, and residue analysis, ≥99.9%, contains 50-150 ppm amylene as stabilizer
Synonym: methylene chloride; Methylene chloride
CAS Number: 75-09-2
Empirical Formula (Hill Notation): CH2Cl2
Molecular Weight: 84.93
EC Number: 200-838-9
MDL Number: MFCD00000881
Linear Formula: CH2Cl2
Product Type: Chemical
| λ | H2O reference |
| assay | ≥99.9% |
| autoignition temp. | 1223 °F |
| bp | 39.8-40 °C (lit.) |
| contains | 50-150 ppm amylene as stabilizer |
| density | 1.325 g/mL at 25 °C (lit.) |
| evapn. residue | ≤0.0001% |
| expl. lim. | 22 % |
| form | liquid |
| grade | HPLC Plus |
| halogenated residue | ≤10 ng/L (as heptachlor epoxide) |
| impurities | ≤ 1.0 ppb Fluorescence (quinine) at 365 nm |
| ≤0.01% water | |
| InChI | 1S/CH2Cl2/c2-1-3/h1H2 |
| InChI key | YMWUJEATGCHHMB-UHFFFAOYSA |
| mp | −95 °C (lit.) |
| Quality Level | 100 ![]() |
| refractive index | n |
| SMILES string | ClCCl |
| suitability | suitable for residue analysis |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| UV absorption | λ: 235 nm Amax: 1.0 |
| λ: 240 nm Amax: 0.10 | |
| λ: 250 nm Amax: 0.02 | |
| λ: 300-400 nm Amax: 0.005 | |
| vapor density | 2.9 (vs air) |
| vapor pressure | 24.45 psi ( 55 °C) |
| 6.83 psi ( 20 °C) |
| Application: | Dichloromethane may be used in the following: • Extraction of neonicotinoids from honey samples along with acetonitrile using dispersive liquid-liquid microextraction (DLLME) • Ultrasonic solvent extraction and clean-up of roasted coffee samples for the analysis of 7 pesticide residues by liquid chromatography-tandem mass spectrometry (LC-MS/MS) • DLLME based additional pre-concentration of the sample extracts in the analysis of three amphenicols in food products of animal origin by HPLC with UV detection • Removal of organic phase of the obtained soil sample extracts in the determination of two sulfonylurea herbicides using HPLC • Testing of four extraction solvents in the development of a HPLC-amperometric detection based method for the analysis of three carbamate residues in liquid and solid food samples • Extraction of metrafenone from vegetable samples by matrix solid-phase dispersion (MSPD method followed by HPLC analysis |
| Application: | Suitable for HPLC, spectrophotometry, environmental testing |
| Legal Information: | Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Other Notes: | Discover LiChropur reagents ideal for HPLC or LC-MS analysis |
| Other Notes: | Pesticide Residue Analysis (as Heptachlor Epoxide) <10 ng/L |
| Other Notes: | Pure-Pac® II containers require the Micromatic MacroValve coupler for dispensing solvents, Z560723. |
| Packaging: | 1, 6×1, 4, 4×4 L in glass bottle |
| Packaging: | 20 L in Nowpak™ II |
| Packaging: | 20 L in Pure-Pac™ 2 |
| Packaging: | M-Bottle for Solvents As a global leader in lab reagents, we are constantly looking for new ways to optimize the safety of our products. The newly developed 4L solvent bottle design features advanced sealing technology that eliminates leaks to make the handling of solvents safer and more convenient than ever before. See all the new features here! ![]() |
| Packaging: | View returnable container options . |
| Symbol | ![]() GHS07,GHS08 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H336 - H351 |
| Precautionary statements | P201 - P202 - P261 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-40-67 |
| Safety Statements | 23-24/25-36/37 |
| RIDADR | UN 1593 6.1 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | does not flash |
| Flash Point(C) | does not flash |
| Purity | ≥99.9% |
| bp | 39.8-40 °C (lit.) |
| mp | −95 °C (lit.) |
| Density | 1.325 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12190000 |



