N,N-Dimethylacetamide
SIGALD/D137510 - ReagentPlus®, 99%
CAS Number: 127-19-5
Empirical Formula (Hill Notation): C4H9NO
Molecular Weight: 87.12
EC Number: 204-826-4
MDL Number: MFCD00008686
Linear Formula: CH3CON(CH3)2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D137510-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: D137510-500ML.
| assay | 99% |
| autoignition temp. | 914 °F |
| bp | 164.5-166 °C (lit.) |
| density | 0.937 g/mL at 25 °C (lit.) |
| expl. lim. | 1.8 %, 100 °F |
| 11.5 %, 160 °F | |
| form | liquid |
| InChI | 1S/C4H9NO/c1-4(6)5(2)3/h1 |
| InChI key | FXHOOIRPVKKKFG-UHFFFAOYSA |
| mp | −20 °C (lit.) |
| pH | 4 (20 °C, 200 g/L) |
| product line | ReagentPlus® |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | CN(C)C(C)=O |
| vapor density | 3 (vs air) |
| vapor pressure | 2 mmHg ( 25 °C) |
| 4 mmHg ( 38 °C) |
| Application: | N,N-Dimethylacetamide can be used as a solvent in the synthesis of: • Cellulose-HA (hydroxyapatite) nanocomposites using microcrystalline cellulose, CaCl2, and NaH2PO4. • 5-hydroxymethylfurfural (HMF) from various carbohydrates and natural biopolymer lignocellulose in the presence of LiCl. It can also be used: • In the Pd-catalyzed regioselective synthesis of ketones from olefins using molecular oxygen. • As a solvent as well as a methylene source in the regioselective linkage of two imidazo[1,2-a] pyridines using Cu(OAc)2 catalyst. |
| Features and Benefits: | N,N-Dimethylacetamide has • High dissolution power of various substrate. • High capacity to solvate anions. |
| General description: | N,N-Dimethylacetamide (DMAc) is a water-miscible organic solvent used in the synthesis of styrene′s, vinyl resins, linear polyesters, acrylic fibers, plastics, pesticides, and synthetic leather. Additionally, it is utilized in the production of adhesives, films, and paint. It participates in dehydrogenation, dehydration, halogenation, deprotonation reactions and reductive carbonylation of transition metals. It can also act as catalysts, promoters, halogen/alkoxy or hydroxyl/halogen exchange mediators, reducing agents, and sources of the base. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Legal Information: | Belle Chemical Company |
| Packaging: | 1, 2.5, 4 L in glass bottle |
| Packaging: | 18, 20 L in steel drum |
| Packaging: | 500 mL in glass bottle |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H312 + H332 - H319 - H360D |
| Precautionary statements | P202 - P280 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-20/21-36 |
| Safety Statements | 53-45 |
| WGK Germany | WGK 2 |
| Flash Point(F) | 147.2 °F - closed cup |
| Flash Point(C) | 64 °C - closed cup |
| Purity | 99% |
| bp | 164.5-166 °C (lit.) |
| mp | −20 °C (lit.) |
| Density | 0.937 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352111 |