1,2-Dimethoxyethane
SIGALD/E27408 - ReagentPlus®, ≥99%, inhibitor-free
Synonym: mono-Glyme; Dimethylglycol; Ethylene glycol dimethyl ether; Monoglyme
CAS Number: 110-71-4
Empirical Formula (Hill Notation): C4H10O2
Molecular Weight: 90.12
EC Number: 203-794-9
MDL Number: MFCD00008502
Linear Formula: CH3OCH2CH2OCH3
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E27408-100ML.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E27408-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E27408-500ML.
| assay | ≥99% |
| autoignition temp. | 396 °F |
| bp | 85 °C (lit.) |
| density | 0.867 g/mL at 25 °C (lit.) |
| dilution | (for general lab use) |
| expl. lim. | 10.4 % |
| form | liquid |
| impurities | ≤0.5% (water) |
| InChI | 1S/C4H10O2/c1-5-3-4-6-2/h |
| InChI key | XTHFKEDIFFGKHM-UHFFFAOYSA |
| mp | −58 °C (lit.) |
| pH | 7 |
| product line | ReagentPlus® |
| Quality Level | 100  |
| refractive index | n |
| SMILES string | COCCOC |
| vapor density | 3.1 (20 °C, vs air) |
| vapor pressure | 48 mmHg ( 20 °C) |
| Application: | 1,2-Dimethoxyethane can be used as a solvent to synthesize:• Oxazoles from α-acylamino ketones via Robinson-Gabriel reaction. • 5-Arylhistidines via Suzuki-Miyaura cross-coupling between 5-bromohistidine and arylboronic acids. • Aryl thioethers via Pd-catalyzed thioetherification of aryl halides with aliphatic and aromatic thiols. |
| General description: | 1,2-Dimethoxyethane (DME) is an inert aprotic polar solvent for electrolytes of lithium batteries, polysilicones, oligo- and polysaccharides. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 1, 4 L in glass bottle |
| Packaging: | 100, 500 mL in glass bottle |
| Packaging: | 18, 20 L in steel drum |
| Symbol |    GHS02,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H315 - H332 - H360FD |
| Precautionary statements | P202 - P210 - P233 - P303 + P361 + P353 - P304 + P340 + P312 - P308 + P313 |
| Hazard Codes | F,T |
| Risk Statements | 60-61-11-19-38 |
| Safety Statements | 53-45 |
| RIDADR | UN 2252 3 / PGII |
| WGK Germany | WGK 1 |
| Flash Point(F) | 41.0 °F - closed cup |
| Flash Point(C) | 5 °C - closed cup |
| Supplemental Hazard Statements | EUH019 |
| Purity | ≥99% |
| bp | 85 °C (lit.) |
| mp | −58 °C (lit.) |
| Density | 0.867 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352112 |