Ruthenium Red
SIGMA/00541 - for microscopy, 85.0-115.0% (calc. on dry basis, AT)
Synonym: Ammoniated ruthenium oxychloride
CAS Number: 11103-72-3
Empirical Formula (Hill Notation): H42Cl6N14O2Ru3
Molecular Weight: 786.35
MDL Number: MFCD00011479
Linear Formula: [(NH3)5RuORu(NH3)4ORu(NH3)5]Cl6
Product Type: Chemical
| εmax | ≥150 at 529-539 nm |
| application(s) | diagnostic assay manufacturing hematology histology |
| assay | 85.0-115.0% (calc. on dry basis, AT) |
| form | powder |
| grade | for microscopy |
| impurities | ~5% water |
| InChI | 1S/6ClH.14H3N.2O.3Ru/h6*1 |
| InChI key | ZXYSDUPLHOJIOR-UHFFFAOYSA |
| Quality Level | 100  |
| SMILES string | N.N.N.N.N.N.N.N.N.N.N.N.N |
| solubility | water: 10 mg/mL, clear to turbid |
| storage temp. | room temp |
| Application: | Inhibits mitochondrial Ca2+ uniporter; capsaicin antagonist; blocks VR1 vanilloid receptor-coupled ion channels. |
| Application: | Ruthenium red is suitable for use in light microscopy to stain pectins. It is also used to stain glycosaminoglycans by employing a two-color staining method with alcian blue. It serves as a typical basic dye at a higher pH that stains nuclei, Nissl substance, cartilage matrix, and mast cell granules. Other applications involving light microscopy include staining resin-embedded material. Ruthenium red is an important component of fixatives of the bacterial glycocalyx. |
| Biochem/physiol Actions: | Ruthenium red inhibits mitochondrial Ca2+ uniporter. It is a known capsaicin antagonist. Additionally, it is known to block VR1 vanilloid receptor-coupled ion channels. |
| General description: | Ruthenium red is an inorganic cationic dye. It is also known as ammoniated ruthenium oxychloride. It is a large coordination complex consisting of three metal atoms connected by bridging oxygens, in addition to multiple amine ligands. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 85.0-115.0% (calc. on dry basis, AT) |
| Storage Temp. | room temp |
| Colour Index Number | 77800 |
| UNSPSC | 12352200 |