Acylase I from Aspergillus melleus
SIGMA/01818 - powder, brown, >0.5 U/mg
Synonym: Acylase ‘Amano’; Aminoacylase
CAS Number: 9012-37-7
EC Number: 232-732-3
MDL Number: MFCD00081285
Product Type: Chemical
| color | brown |
| form | powder |
| Quality Level | 100  |
| specific activity | >0.5 U/mg |
| storage temp. | 2-8°C |
| Analysis Note: | Enzyme activity: the optimum temperature is 40-45°C, the optimum pH is 8.0 (stable form pH 6-10). The enzyme is activated by CoCl2 in the range of 10-4 to 10-3 M. |
| Application: | Acylase I from Aspergillus melleus has been used to catalyze the Mannich reaction. |
| Biochem/physiol Actions: | Acylase I plays an important role in the amino acid metabolism of organisms. It also plays a role in the acylation of primary and secondary alcohols. Acylase I is involved in alcoholysis. |
| General description: | Acylase I belongs to the aminoacylase family of enzymes. |
| Other Notes: | Resolution of acetyl amino acids |
| Unit Definition: | 1 U corresponds to the amount of enzyme which hydrolyzes 1 μmol N-acetyl-L-methionine per minute at pH 8.0 and 37°C |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H315 - H319 - H334 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 36/37/38-42 |
| Safety Statements | 22-24-26-36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| activity | specific activity: >0.5 U/mg |
| Storage Temp. | 2-8°C |
| Enzyme Commission (EC) Number | 3.5.1.14 ( BRENDA  | IUBMB ) |
| UNSPSC | 12352204 |