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Tioconazole

SIGMA/03907 - 97%

Synonym: 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole; Thioconazole

CAS Number: 65899-73-2
Empirical Formula (Hill Notation): C16H13Cl3N2OS
Molecular Weight: 387.71
EC Number: 265-973-8
MDL Number: MFCD00057276
Linear Formula: C16H13Cl3N2OS
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-03907-10G 10 g
$183.00
1/EA
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antibiotic activity spectrum fungi
  yeast
assay ≥96.5% (HPLC)
  96.5-103.5% (NT)
  97%
color white to off-white
form powder
InChI 1S/C16H13Cl3N2OS/c17-12-1-2-13(14(18)7-12)15(8-21-5-4-20-10-21)22-9-11-3-6-23-16(11)19/h1-7,10,15H,8-9H2
InChI key QXHHHPZILQDDPS-UHFFFAOYSA-N
mode of action cell membrane | interferes
Quality Level 100 
SMILES string Clc1ccc(C(Cn2ccnc2)OCc3ccsc3Cl)c(Cl)c1
Application: Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.
Biochem/physiol Actions: Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.
General description: Chemical structure: pyrimidine
Other Notes: Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
Packaging: 10G
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Hazard Codes Xn
Risk Statements 22
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥96.5% (HPLC); 96.5-103.5% (NT); 97%
UNSPSC 51101500

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