L-Alanine

SIGMA/05129 - BioUltra, ≥99.5% (NT)

Synonym: (S)-2-Aminopropionic acid; L-α-Aminopropionic acid

CAS Number: 56-41-7
Empirical Formula (Hill Notation): C₃H₇NO₂
Molecular Weight: 89.09
EC Number: 200-273-8
MDL Number: MFCD00064410
Linear Formula: C₃H₇NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-05129-25G	25 g	$83.10 1/EA	Add To Favorites
45-05129-100G	100 g	$294.00 1/EA	Add To Favorites
45-05129-500G	500 g	$962.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

λ	1 M in H₂O
anion traces	chloride (Cl^-): ≤50 mg/kg
	sulfate (SO₄^2-): ≤50 mg/kg
application(s)	detection
assay	≥99.5% (NT)
cation traces	Al: ≤5 mg/kg
	As: ≤0.1 mg/kg
	Ba: ≤5 mg/kg
	Bi: ≤5 mg/kg
	Ca: ≤10 mg/kg
	Cd: ≤5 mg/kg
	Co: ≤5 mg/kg
	Cr: ≤5 mg/kg
	Cu: ≤5 mg/kg
	Fe: ≤5 mg/kg
	K: ≤50 mg/kg
	Li: ≤5 mg/kg
	Mg: ≤5 mg/kg
	Mn: ≤5 mg/kg
	Mo: ≤5 mg/kg
	Na: ≤50 mg/kg
	NH₄⁺: ≤100 mg/kg
	Ni: ≤5 mg/kg
	Pb: ≤5 mg/kg
	Sr: ≤5 mg/kg
	Zn: ≤5 mg/kg
color	colorless to white
form	powder or crystals
ign. residue	≤0.05%
impurities	insoluble matter, passes filter test
	≤0.3% foreign amino acids
InChI	1S/C3H7NO2/c1-2(4)3(5)6/h2H,4H2,1H3,(H,5,6)/t2-/m0/s1
InChI key	QNAYBMKLOCPYGJ-REOHCLBHSA-N
loss	≤0.05% loss on drying, 20 °C (HV)
mp	314.5 °C
optical activity	[α]20/D +14.0±1.0°, c = 5% in 5 M HCl
pH	5.5-7.0 (25 °C, 1 M in H₂O)
product line	BioUltra
Quality Level	200
SMILES string	C[C@H](N)C(O)=O
solubility	H₂O: 1 M at 20 °C, clear, colorless
UV absorption	λ: 260 nm A_max: ≤0.03
	λ: 280 nm A_max: ≤0.02

Application:	A Color Indicator Based on 3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide (MTT) and a Biodegradable Poly(ester amide) for Detecting Bacterial Contamination.: This study developed a biodegradable poly(ester amide) containing L-Alanine used with MTT for the detection of bacterial contamination, highlighting its potential in health-related applications (Franco et al., 2024 ). Randomized Trial to Assess the Safety and Tolerability of Daily Intake of an Allulose Amino Acid-Based Hydration Beverage in Men and Women.: Investigates the impact of a daily hydration beverage supplemented with L-Alanine among other amino acids on hydration and nutrient uptake in humans, emphasizing its safety and efficacy (Bloomer et al., 2024 ). Comparison of methods for the NMR measurement of motionally averaged dipolar couplings.: This study utilizes L-Alanine samples to compare NMR methods for measuring dipolar couplings, contributing to the improvement of NMR spectroscopy techniques (Southern et al., 2024 ).
Biochem/physiol Actions:	Alanine is a nonessential amino acid that plays a key role in the glucose-alanine cycle between muscle tissue and the liver. In amino acid-degrading tissues such as muscle, amino groups are pooled as glutamate by transamination reactions. The amino group of glutamate is transferred to pyruvate via alanine aminotransferase, forming alanine and α-ketoglutarate. The alanine is passed into the blood and transported to the liver. This reaction is reversed in the liver where pyruvate can be used in gluconeogenesis to form glucose, which may return to other tissues through the circulatory system. Increased alanine levels correlate with higher blood pressure, energy intake, cholesterol levels, and body mass index.
Other Notes:	Postulated salting-in effect on proteins; Growth requirement of a variety of microorganisms.

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.5% (NT)
mp	314.5 °C
UNSPSC	12352209

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