2-Aminoacridone

SIGMA/06627 - BioReagent, suitable for fluorescence, ≥98.0% (HPLC)

Synonym: 2-Amino-9(10H)-acridinone; 2-amino-10H-acridin-9-one; AMAC

CAS Number: 27918-14-5
Empirical Formula (Hill Notation): C₁₃H₁₀N₂O
Molecular Weight: 210.23
MDL Number: MFCD00037397
Linear Formula: C₁₃H₁₀N₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-06627-25MG	25 mg	$145.00 1/EAAdd To Favorites		Add To Favorites
45-06627-100MG	100 mg	$413.00 1/EAAdd To Favorites		Add To Favorites

assay	≥98.0% (HPLC)
fluorescence	λ_ex 420 nm; λ_em 542 nm in 0.1 M Tris pH 8.0
InChI	1S/C13H10N2O/c14-8-5-6-12-10(7-8)13(16)9-3-1-2-4-11(9)15-12/h1-7H,14H2,(H,15,16)
InChI key	PIGCSKVALLVWKU-UHFFFAOYSA-N
product line	BioReagent
Quality Level	100
SMILES string	Nc1ccc2Nc3ccccc3C(=O)c2c1
solubility	DMF: soluble
	DMSO: soluble
suitability	suitable for fluorescence

Application:	2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH₄). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides . The λ excitation and λ emission are 425 nm and 532 nm, respectively.
Application:	Fluorescent label for glycans and saccharides.
Packaging:	Bottomless glass bottle. Contents are inside inserted fused cone.

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable