2-Aminoacridone
SIGMA/06627 - BioReagent, suitable for fluorescence, ≥98.0% (HPLC)
Synonym: 2-
CAS Number: 27918-14-5
Empirical Formula (Hill Notation): C13H10N2O
Molecular Weight: 210.23
MDL Number: MFCD00037397
Linear Formula: C13H10N2O
Product Type: Chemical
assay | ≥98.0% (HPLC) |
fluorescence | λex 420 nm; λem 542 nm in 0.1 M Tris pH 8.0 |
InChI | 1S/C13H10N2O/c14-8-5-6-12 |
InChI key | PIGCSKVALLVWKU-UHFFFAOYSA |
product line | BioReagent |
Quality Level | 100 |
SMILES string | Nc1ccc2Nc3ccccc3C(=O)c2c1 |
solubility | DMF: soluble |
DMSO: soluble | |
suitability | suitable for fluorescence |
Application: | 2-Aminoacridone is a highly fluorescent aromatic, which contains a primary amine group that reacts with an aldehyde group at the reducing end of a carbohydrate and is reduced to a stable amine derivative by sodium borohydride (NaBH4). Picomolar levels of glycan compounds can be detected using this fluorophore. The resulting derivatzed compounds can be separated by reverse-phase HPLC and detected by positive-ion electrospray MS . An intense fluorescent, hydrophobic probe that is stable over a wide pH range is useful in the derivatization of glycans to allow for the analysis of complex oligosaccharides using micellar electrokinetic capillary chromatography and reverse- and normal-phase chromatography coupled with mass spectroscopy to determine relative concentrations and structural identity of individual oligosaccharides . The λ excitation and λ emission are 425 nm and 532 nm, respectively. |
Application: | Fluorescent label for glycans and saccharides. |
Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H315 - H319 - H335 |
Precautionary statements | P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36/37/38 |
Safety Statements | 26-36 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98.0% (HPLC) |
UNSPSC | 12352200 |